Figure A3. Historical datasets considered in the simulation study. Observed Kaplan-Meier curves of SARC-OS patients, that is, the subgroup of OS2006 patients satisfying the Sarcome-13 trial eligibility criteria, and Kaplan-Meier curves of the two hypothetical historical datasets: one simulated from a Weibull distribution and one from a piecewise exponential distribution. (PDF 115 kb
Table S2. Mean number of additionally included prognostic variables for all scenarios with K=24. (PD...
Table S1. Mean number of additionally included prognostic variables for all scenarios with K=12. (PD...
International audienceBACKGROUND:Performing well-powered randomised controlled trials (RCTs) of new ...
Figure A2. Subgroup of OS2006 historical data (SARC-OS data). Observed Kaplan-Meier and parametric e...
Motivating example: the Sarcome-13 trial. Context and design of the Sarcome-13 trial. This document ...
Figure A4-A6. Graphical representation of scenarios S1 to S32. Graphical representations of scenario...
Tables A13-A16. Impact of α0 and ω on the operating characteristics for scenarios S25 to S32 when th...
Figure A7. Posterior distribution of the log-hazard ratio depending on the values of the weighting p...
Tables A1-A3. Impact of α0 and ω on the operating characteristics for scenarios S1 to S12. These tab...
Likelihood of the distributions used. Description of the likelihood of a Weibull proportional hazard...
Tables A7-A12. Impact of α0 and ω on the operating characteristics for scenarios S1 to S12 when σ H ...
Figure A1. Mixture prior distribution of the treatment effect for different values of ω. Mixture pri...
Table S1. TPR, FPR and FDR in variable selection with 50 replications (Weibull distribution). Table ...
R code of to compute the posterior joint distribution in the context of a Bayesian Weibull model (PD...
Table S3. Mean number of additionally included prognostic variables for all scenarios with K=36. (PD...
Table S2. Mean number of additionally included prognostic variables for all scenarios with K=24. (PD...
Table S1. Mean number of additionally included prognostic variables for all scenarios with K=12. (PD...
International audienceBACKGROUND:Performing well-powered randomised controlled trials (RCTs) of new ...
Figure A2. Subgroup of OS2006 historical data (SARC-OS data). Observed Kaplan-Meier and parametric e...
Motivating example: the Sarcome-13 trial. Context and design of the Sarcome-13 trial. This document ...
Figure A4-A6. Graphical representation of scenarios S1 to S32. Graphical representations of scenario...
Tables A13-A16. Impact of α0 and ω on the operating characteristics for scenarios S25 to S32 when th...
Figure A7. Posterior distribution of the log-hazard ratio depending on the values of the weighting p...
Tables A1-A3. Impact of α0 and ω on the operating characteristics for scenarios S1 to S12. These tab...
Likelihood of the distributions used. Description of the likelihood of a Weibull proportional hazard...
Tables A7-A12. Impact of α0 and ω on the operating characteristics for scenarios S1 to S12 when σ H ...
Figure A1. Mixture prior distribution of the treatment effect for different values of ω. Mixture pri...
Table S1. TPR, FPR and FDR in variable selection with 50 replications (Weibull distribution). Table ...
R code of to compute the posterior joint distribution in the context of a Bayesian Weibull model (PD...
Table S3. Mean number of additionally included prognostic variables for all scenarios with K=36. (PD...
Table S2. Mean number of additionally included prognostic variables for all scenarios with K=24. (PD...
Table S1. Mean number of additionally included prognostic variables for all scenarios with K=12. (PD...
International audienceBACKGROUND:Performing well-powered randomised controlled trials (RCTs) of new ...