Data_Sheet_1_Prevalence of Antibiotic and Heavy Metal Resistance Determinants and Virulence-Related Genetic Elements in Plasmids of Staphylococcus aureus.pdf

  • Michal Bukowski (5724209)
  • Rafal Piwowarczyk (6628250)
  • Anna Madry (6628253)
  • Rafal Zagorski-Przybylo (6628256)
  • Marcin Hydzik (5724212)
  • Benedykt Wladyka (160387)
Publication date
April 2019
Publisher
Frontiers Media SA

Abstract

The use of antibiotics on a mass scale, particularly in farming, and their release into the environment has led to a rapid emergence of resistant bacteria. Once emerged, resistance determinants are spread by horizontal gene transfer among strains of the same as well as disparate bacterial species. Their accumulation in free-living as well as livestock and community-associated strains results in the widespread multiple-drug resistance among clinically relevant species posing an increasingly pressing problem in healthcare. One of these clinically relevant species is Staphylococcus aureus, a common cause of hospital and community outbreaks. Among the rich diversity of mobile genetic elements regularly occurring in S. aureus such as phages, pat...

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