Additional file 1: of Beta-blockers for the primary prevention of anthracycline-induced cardiotoxicity: a meta-analysis of randomized controlled trials

Supplementary Methods. Figure S1. Flow chart showing the process of study selection and numbers of studies included. Figure S2. Risk of reporting bias for each study included in this meta-analysis. Figure S3. Assessment of publication bias by the funnel plot. Figure S4. Forest plot with individual and summary estimates of the mean difference (MD) and 95% confidence interval (CI) of LV diastolic functions. Figure S5. Forest plot with individual and summary estimates of the risk ratio (RR) and 95% confidence interval (CI) of adverse events. Figure S6. Forest plot with individual and summary estimates of the mean difference (MD) and 95% confidence interval (CI) of LV systolic and diastolic functions in the substudy for patients with non-selective β blockers. Figure S7. Forest plot with individual and summary estimates of the mean difference (MD) and 95% confidence interval (CI) of LV systolic and diastolic functions in the substudy for patients with selective β blockers. (DOCX 1924 kb