Level of ATP normalized by cell viability (A) and oxidative stress (B-C) were determined at different time points. Representative pictures are showing TH expressing neurons with low level of ROS (left panel) or high level of ROS (right panel). A value of 1 corresponds to the mean intensity of luminescence in the vehicle condition (ATP) or to 5 +/- 1 neurons (ROS). All values were expressed as mean +/- SEM; n = 6/group; *, p<0,05 with One-way ANOVA followed by Dunnett’s test.</p
As a first step towards designing a cell line model to study mitochondrial disease we require tools ...
<p><b><i>(A)</i></b> Mitochondrial membrane potential in Daudi cells and PBMCs with and without Mito...
<p>ROS production was estimated by oxidation of the fluorescent probes MitoSox in U251, U251-ρ° and ...
<p>(A) ROS levels were assessed in cells preloaded with an oxidation sensitive fluorophore following...
<p>(A) Simulated time-courses for mitochondrial membrane potential (ψm). Gradual ROS inhibition from...
<p>Mitochondrial membrane potential (<b>A</b>), ATP levels (<b>B</b>), and mitochondrial ROS (<b>C</...
<p>HUVECs were pretreated with various Dp concentrations (1, 10, 50 and 100 μM, respectively) for 2 ...
<p>(A) Detection of mitochondrial ROS in live cells. Live MSCs were treated with Ara-C (100 mM for 2...
<p>UMR-106 cells were treated, as described above, and stained with JC-1 or DCFH-DA. Subsequently, t...
<p>(A) Model predictions were obtained by plotting the intensity for each readout (membrane potentia...
<p>Quantitative analysis of changes in mean fluorescence intensity of mitochondrial superoxide sensi...
<p>(A) Representative images of Mitosox red staining. (B) Level of mitochondrial ROS was assessed by...
Mitochondrial reactive oxygen species (ROS) are implicated in signal transduction, inflammation, neu...
Drug-induced mitochondrial toxicity is considered as a common cellular mechanism that can induce a v...
<p>A) Flow cytometry histogram showing change in ROS level after exposure to γ, and <sup>56</sup>Fe ...
As a first step towards designing a cell line model to study mitochondrial disease we require tools ...
<p><b><i>(A)</i></b> Mitochondrial membrane potential in Daudi cells and PBMCs with and without Mito...
<p>ROS production was estimated by oxidation of the fluorescent probes MitoSox in U251, U251-ρ° and ...
<p>(A) ROS levels were assessed in cells preloaded with an oxidation sensitive fluorophore following...
<p>(A) Simulated time-courses for mitochondrial membrane potential (ψm). Gradual ROS inhibition from...
<p>Mitochondrial membrane potential (<b>A</b>), ATP levels (<b>B</b>), and mitochondrial ROS (<b>C</...
<p>HUVECs were pretreated with various Dp concentrations (1, 10, 50 and 100 μM, respectively) for 2 ...
<p>(A) Detection of mitochondrial ROS in live cells. Live MSCs were treated with Ara-C (100 mM for 2...
<p>UMR-106 cells were treated, as described above, and stained with JC-1 or DCFH-DA. Subsequently, t...
<p>(A) Model predictions were obtained by plotting the intensity for each readout (membrane potentia...
<p>Quantitative analysis of changes in mean fluorescence intensity of mitochondrial superoxide sensi...
<p>(A) Representative images of Mitosox red staining. (B) Level of mitochondrial ROS was assessed by...
Mitochondrial reactive oxygen species (ROS) are implicated in signal transduction, inflammation, neu...
Drug-induced mitochondrial toxicity is considered as a common cellular mechanism that can induce a v...
<p>A) Flow cytometry histogram showing change in ROS level after exposure to γ, and <sup>56</sup>Fe ...
As a first step towards designing a cell line model to study mitochondrial disease we require tools ...
<p><b><i>(A)</i></b> Mitochondrial membrane potential in Daudi cells and PBMCs with and without Mito...
<p>ROS production was estimated by oxidation of the fluorescent probes MitoSox in U251, U251-ρ° and ...