Low genetic heterogeneity of copy number variations (CNVs) in the genes encoding the human deoxyribonucleases 1-like 3 and II potentially relevant to autoimmunity - Fig 1

The CNVs in (A) DNASE1L3 and (B) DNASE2. The genomic structures of each DNase gene were based upon the NCBI Reference Sequence: NG_032070.1 and NC_000019.10, respectively. All the CNVs in each gene were registered in the Database of Genomic Variants (http://dgv.tcag.ca/gb2/gbrowse/dgv2_hg38/). The black and gray bars indicate gain and loss of copy, respectively, in the CNVs. The regions of the gene shown by the dashed lines are the target regions used for Q-PCR analysis of each gene.