Additional file 6: of PIK3CA activating mutations are associated with more disseminated disease at presentation and earlier recurrence in glioblastoma

Additional file 6: of Targeted next-generation sequencing identifies clinically relevant somatic mutations in a large cohort of inflammatory breast cancer

Xu Liang (433535)
Sophie Vacher (233965)
Anais Boulai (5612039)
Virginie Bernard (2226220)
Sylvain Baulande (5113562)
Mylene Bohec (5612042)
Ivan BiĂ¨che (5506235)
Florence Lerebours (303656)
CĂŠline Callens (5612045)

August 2018

Figure S4. MFS curves stratified by PIK3CA mutation in three subgroups of IBC patients. (a) Kaplan-M...

Additional file 3: of The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the Î˛-catenin/SIRT3 signaling pathway in cervical cancer

Wei Jiang (14986)
Tiancong He (5495273)
Shuai Liu (145969)
Yingying Zheng (400158)
Libing Xiang (767188)
Xuan Pei (5495270)
Ziliang Wang (482117)
Huijuan Yang (767190)

December 2018

Figure S2. The expression of other key glycolytic enzymes after knocking down the expression of Î˛-c...

Additional file 3: of Clinical evaluation of a dedicated next generation sequencing panel for routine glioma diagnostics

Nathalie Synhaeve (6005657)
Martin van den Bent (3487037)
Pim French (3487031)
Winand Dinjens (6005660)
Peggy Atmodimedjo (6005663)
Johan Kros (3629321)
R. Verdijk (6005666)
Clemens Dirven (568812)
Hendrikus Dubbink (6005669)

November 2018

Figure S2a-c. A 38âyear old female presented with burn-out complaints and several episodes suggest...

Additional file 4: of PIK3CA activating mutations are associated with more disseminated disease at presentation and earlier recurrence in glioblastoma

Shota Tanaka (339198)
Tracy Batchelor (6648710)
A. Iafrate (6648713)
Dora Dias-Santagata (128565)
Darrell Borger (192022)
Leif Ellisen (6648716)
Daniel Yang (584075)
David Louis (6648725)
Daniel Cahill (5868119)
Andrew Chi (6648728)

April 2019

Figure S4. Kaplan-Meier curves of OS in IDH1 wildtype glioblastomas stratified by PIK3CA mutation. P...

Additional file 3: of PIK3CA activating mutations are associated with more disseminated disease at presentation and earlier recurrence in glioblastoma

Shota Tanaka (339198)
Tracy Batchelor (6648710)
A. Iafrate (6648713)
Dora Dias-Santagata (128565)
Darrell Borger (192022)
Leif Ellisen (6648716)
Daniel Yang (584075)
David Louis (6648725)
Daniel Cahill (5868119)
Andrew Chi (6648728)

April 2019

Figure S3. Kaplan-Meier curves of PFS in IDH1 wildtype glioblastomas stratified by PIK3CA mutation. ...

Additional file 2: of PIK3CA activating mutations are associated with more disseminated disease at presentation and earlier recurrence in glioblastoma

Shota Tanaka (339198)
Tracy Batchelor (6648710)
A. Iafrate (6648713)
Dora Dias-Santagata (128565)
Darrell Borger (192022)
Leif Ellisen (6648716)
Daniel Yang (584075)
David Louis (6648725)
Daniel Cahill (5868119)
Andrew Chi (6648728)

April 2019

Figure S2. Kaplan-Meier curves of OS stratified by PIK3CA mutation. PIK3CA mutant tumors (solid) and...

Additional file 5: of PIK3CA activating mutations are associated with more disseminated disease at presentation and earlier recurrence in glioblastoma

Shota Tanaka (339198)
Tracy Batchelor (6648710)
A. Iafrate (6648713)
Dora Dias-Santagata (128565)
Darrell Borger (192022)
Leif Ellisen (6648716)
Daniel Yang (584075)
David Louis (6648725)
Daniel Cahill (5868119)
Andrew Chi (6648728)

April 2019

Figure S5. Kaplan-Meier curves of PFS stratified by PIK3CA mutation in the TCGA cohort. PIK3CA mutan...

Additional file 1: of PIK3CA activating mutations are associated with more disseminated disease at presentation and earlier recurrence in glioblastoma

Shota Tanaka (339198)
Tracy Batchelor (6648710)
A. Iafrate (6648713)
Dora Dias-Santagata (128565)
Darrell Borger (192022)
Leif Ellisen (6648716)
Daniel Yang (584075)
David Louis (6648725)
Daniel Cahill (5868119)
Andrew Chi (6648728)

April 2019

Figure S1. Kaplan-Meier curves of OS and PFS stratified by established molecular prognostic factors ...

Additional file 1: of PI3 kinase mutations and mutational load as poor prognostic markers in diffuse glioma patients

Kaspar Draaisma (3487046)
Maarten Wijnenga (3487040)
Bas Weenink (3487034)
Ya Gao (526722)
Marcel Smid (54590)
P. Robe (3487043)
Martin van den Bent (3487037)
Pim French (3487031)

December 2015

Table S1. Genetic changes associated with survival in the entire TCGA (GBM and LGG) datasets. Table ...

Additional file 2: of PI3 kinase mutations and mutational load as poor prognostic markers in diffuse glioma patients

Kaspar Draaisma (3487046)
Maarten Wijnenga (3487040)
Bas Weenink (3487034)
Ya Gao (526722)
Marcel Smid (54590)
P. Robe (3487043)
Martin van den Bent (3487037)
Pim French (3487031)

December 2015

Figure S1. PI3-kinase mutations are prognostic for survival in independent datasets. Figure S2. Surv...

Additional file 3: of TERT promoter wild-type glioblastomas show distinct clinical features and frequent PI3K pathway mutations

Erik Williams (5868107)
Julie Miller (2948109)
Shilpa Tummala (5868110)
Tristan Penson (5868113)
A. John Iafrate (128597)
Tareq Juratli (5868116)
Daniel Cahill (5868119)

October 2018

A table listing all detected PI3K alterations in the cohort. The majority of alterations were report...

Additional file 5: of The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the Î˛-catenin/SIRT3 signaling pathway in cervical cancer

Wei Jiang (14986)
Tiancong He (5495273)
Shuai Liu (145969)
Yingying Zheng (400158)
Libing Xiang (767188)
Xuan Pei (5495270)
Ziliang Wang (482117)
Huijuan Yang (767190)

December 2018

Figure S4. The correlation analysis between Î˛-catenin and SIRT3 in cervical cancer tissues with wil...

Additional file 4: of The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the Î˛-catenin/SIRT3 signaling pathway in cervical cancer

Wei Jiang (14986)
Tiancong He (5495273)
Shuai Liu (145969)
Yingying Zheng (400158)
Libing Xiang (767188)
Xuan Pei (5495270)
Ziliang Wang (482117)
Huijuan Yang (767190)

December 2018

Figure S3. The correlation analysis between Î˛-catenin and SIRT3 by western blotting in SiHa and MS7...

Additional file 2: of The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the Î˛-catenin/SIRT3 signaling pathway in cervical cancer

Wei Jiang (14986)
Tiancong He (5495273)
Shuai Liu (145969)
Yingying Zheng (400158)
Libing Xiang (767188)
Xuan Pei (5495270)
Ziliang Wang (482117)
Huijuan Yang (767190)

December 2018

Figure S1. Relative mRNA expression of other glycolytic enzymes in SiHa and MS751 cells with wild-ty...

Additional file 3: Figure S1. of Characterizing temporal genomic heterogeneity in pediatric high-grade gliomas

Ralph Salloum (4544821)
Melissa McConechy (267180)
Leonie Mikael (4544809)
Christine Fuller (4544812)
Rachid Drissi (4544830)
Mariko DeWire (4544842)
Hamid Nikbakht (3275400)
Nicolas De Jay (668372)
Xiaodan Yang (746617)
Daniel Boue (4544806)
Lionel Chow (4544827)
Jonathan Finlay (4544833)
Tenzin Gayden (4544839)
Jason Karamchandani (4544797)
Trent Hummel (4544815)
Randal Olshefski (4544818)
Diana Osorio (4544836)
Charles Stevenson (4544803)
Claudia Kleinman (3926051)
Jacek Majewski (65417)
Maryam Fouladi (4544800)
Nada Jabado (4544824)

October 2017

IGV views a subclonal low frequency PIK3CA mutation in HGG3 from a clinical sequencing panel, WES, a...

Additional file 6: of Targeted next-generation sequencing identifies clinically relevant somatic mutations in a large cohort of inflammatory breast cancer

Xu Liang (433535)
Sophie Vacher (233965)
Anais Boulai (5612039)
Virginie Bernard (2226220)
Sylvain Baulande (5113562)
Mylene Bohec (5612042)
Ivan BiĂ¨che (5506235)
Florence Lerebours (303656)
CĂŠline Callens (5612045)

August 2018

Figure S4. MFS curves stratified by PIK3CA mutation in three subgroups of IBC patients. (a) Kaplan-M...

Additional file 3: of The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the Î˛-catenin/SIRT3 signaling pathway in cervical cancer

Wei Jiang (14986)
Tiancong He (5495273)
Shuai Liu (145969)
Yingying Zheng (400158)
Libing Xiang (767188)
Xuan Pei (5495270)
Ziliang Wang (482117)
Huijuan Yang (767190)

December 2018

Figure S2. The expression of other key glycolytic enzymes after knocking down the expression of Î˛-c...

Additional file 3: of Clinical evaluation of a dedicated next generation sequencing panel for routine glioma diagnostics

Nathalie Synhaeve (6005657)
Martin van den Bent (3487037)
Pim French (3487031)
Winand Dinjens (6005660)
Peggy Atmodimedjo (6005663)
Johan Kros (3629321)
R. Verdijk (6005666)
Clemens Dirven (568812)
Hendrikus Dubbink (6005669)

November 2018

Figure S2a-c. A 38âyear old female presented with burn-out complaints and several episodes suggest...

Additional file 4: of PIK3CA activating mutations are associated with more disseminated disease at presentation and earlier recurrence in glioblastoma

Shota Tanaka (339198)
Tracy Batchelor (6648710)
A. Iafrate (6648713)
Dora Dias-Santagata (128565)
Darrell Borger (192022)
Leif Ellisen (6648716)
Daniel Yang (584075)
David Louis (6648725)
Daniel Cahill (5868119)
Andrew Chi (6648728)

April 2019

Figure S4. Kaplan-Meier curves of OS in IDH1 wildtype glioblastomas stratified by PIK3CA mutation. P...

Additional file 3: of PIK3CA activating mutations are associated with more disseminated disease at presentation and earlier recurrence in glioblastoma

Shota Tanaka (339198)
Tracy Batchelor (6648710)
A. Iafrate (6648713)
Dora Dias-Santagata (128565)
Darrell Borger (192022)
Leif Ellisen (6648716)
Daniel Yang (584075)
David Louis (6648725)
Daniel Cahill (5868119)
Andrew Chi (6648728)

April 2019

Figure S3. Kaplan-Meier curves of PFS in IDH1 wildtype glioblastomas stratified by PIK3CA mutation. ...

Additional file 2: of PIK3CA activating mutations are associated with more disseminated disease at presentation and earlier recurrence in glioblastoma

Shota Tanaka (339198)
Tracy Batchelor (6648710)
A. Iafrate (6648713)
Dora Dias-Santagata (128565)
Darrell Borger (192022)
Leif Ellisen (6648716)
Daniel Yang (584075)
David Louis (6648725)
Daniel Cahill (5868119)
Andrew Chi (6648728)

April 2019

Figure S2. Kaplan-Meier curves of OS stratified by PIK3CA mutation. PIK3CA mutant tumors (solid) and...

Additional file 5: of PIK3CA activating mutations are associated with more disseminated disease at presentation and earlier recurrence in glioblastoma

Shota Tanaka (339198)
Tracy Batchelor (6648710)
A. Iafrate (6648713)
Dora Dias-Santagata (128565)
Darrell Borger (192022)
Leif Ellisen (6648716)
Daniel Yang (584075)
David Louis (6648725)
Daniel Cahill (5868119)
Andrew Chi (6648728)

April 2019

Figure S5. Kaplan-Meier curves of PFS stratified by PIK3CA mutation in the TCGA cohort. PIK3CA mutan...

Additional file 1: of PIK3CA activating mutations are associated with more disseminated disease at presentation and earlier recurrence in glioblastoma

Shota Tanaka (339198)
Tracy Batchelor (6648710)
A. Iafrate (6648713)
Dora Dias-Santagata (128565)
Darrell Borger (192022)
Leif Ellisen (6648716)
Daniel Yang (584075)
David Louis (6648725)
Daniel Cahill (5868119)
Andrew Chi (6648728)

April 2019

Figure S1. Kaplan-Meier curves of OS and PFS stratified by established molecular prognostic factors ...

Additional file 1: of PI3 kinase mutations and mutational load as poor prognostic markers in diffuse glioma patients

Kaspar Draaisma (3487046)
Maarten Wijnenga (3487040)
Bas Weenink (3487034)
Ya Gao (526722)
Marcel Smid (54590)
P. Robe (3487043)
Martin van den Bent (3487037)
Pim French (3487031)

December 2015

Table S1. Genetic changes associated with survival in the entire TCGA (GBM and LGG) datasets. Table ...

Additional file 2: of PI3 kinase mutations and mutational load as poor prognostic markers in diffuse glioma patients

Kaspar Draaisma (3487046)
Maarten Wijnenga (3487040)
Bas Weenink (3487034)
Ya Gao (526722)
Marcel Smid (54590)
P. Robe (3487043)
Martin van den Bent (3487037)
Pim French (3487031)

December 2015

Figure S1. PI3-kinase mutations are prognostic for survival in independent datasets. Figure S2. Surv...

Additional file 3: of TERT promoter wild-type glioblastomas show distinct clinical features and frequent PI3K pathway mutations

Erik Williams (5868107)
Julie Miller (2948109)
Shilpa Tummala (5868110)
Tristan Penson (5868113)
A. John Iafrate (128597)
Tareq Juratli (5868116)
Daniel Cahill (5868119)

October 2018

A table listing all detected PI3K alterations in the cohort. The majority of alterations were report...

Additional file 5: of The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the Î˛-catenin/SIRT3 signaling pathway in cervical cancer

Wei Jiang (14986)
Tiancong He (5495273)
Shuai Liu (145969)
Yingying Zheng (400158)
Libing Xiang (767188)
Xuan Pei (5495270)
Ziliang Wang (482117)
Huijuan Yang (767190)

December 2018

Figure S4. The correlation analysis between Î˛-catenin and SIRT3 in cervical cancer tissues with wil...

Additional file 4: of The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the Î˛-catenin/SIRT3 signaling pathway in cervical cancer

Wei Jiang (14986)
Tiancong He (5495273)
Shuai Liu (145969)
Yingying Zheng (400158)
Libing Xiang (767188)
Xuan Pei (5495270)
Ziliang Wang (482117)
Huijuan Yang (767190)

December 2018

Figure S3. The correlation analysis between Î˛-catenin and SIRT3 by western blotting in SiHa and MS7...

Additional file 2: of The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the Î˛-catenin/SIRT3 signaling pathway in cervical cancer

Wei Jiang (14986)
Tiancong He (5495273)
Shuai Liu (145969)
Yingying Zheng (400158)
Libing Xiang (767188)
Xuan Pei (5495270)
Ziliang Wang (482117)
Huijuan Yang (767190)

December 2018

Figure S1. Relative mRNA expression of other glycolytic enzymes in SiHa and MS751 cells with wild-ty...

Additional file 3: Figure S1. of Characterizing temporal genomic heterogeneity in pediatric high-grade gliomas

Ralph Salloum (4544821)
Melissa McConechy (267180)
Leonie Mikael (4544809)
Christine Fuller (4544812)
Rachid Drissi (4544830)
Mariko DeWire (4544842)
Hamid Nikbakht (3275400)
Nicolas De Jay (668372)
Xiaodan Yang (746617)
Daniel Boue (4544806)
Lionel Chow (4544827)
Jonathan Finlay (4544833)
Tenzin Gayden (4544839)
Jason Karamchandani (4544797)
Trent Hummel (4544815)
Randal Olshefski (4544818)
Diana Osorio (4544836)
Charles Stevenson (4544803)
Claudia Kleinman (3926051)
Jacek Majewski (65417)
Maryam Fouladi (4544800)
Nada Jabado (4544824)

October 2017

IGV views a subclonal low frequency PIK3CA mutation in HGG3 from a clinical sequencing panel, WES, a...

Additional file 6: of Targeted next-generation sequencing identifies clinically relevant somatic mutations in a large cohort of inflammatory breast cancer

Xu Liang (433535)
Sophie Vacher (233965)
Anais Boulai (5612039)
Virginie Bernard (2226220)
Sylvain Baulande (5113562)
Mylene Bohec (5612042)
Ivan BiĂ¨che (5506235)
Florence Lerebours (303656)
CĂŠline Callens (5612045)

August 2018

Figure S4. MFS curves stratified by PIK3CA mutation in three subgroups of IBC patients. (a) Kaplan-M...

Additional file 3: of The PIK3CA E542K and E545K mutations promote glycolysis and proliferation via induction of the Î˛-catenin/SIRT3 signaling pathway in cervical cancer

Wei Jiang (14986)
Tiancong He (5495273)
Shuai Liu (145969)
Yingying Zheng (400158)
Libing Xiang (767188)
Xuan Pei (5495270)
Ziliang Wang (482117)
Huijuan Yang (767190)

December 2018

Figure S2. The expression of other key glycolytic enzymes after knocking down the expression of Î˛-c...

Additional file 3: of Clinical evaluation of a dedicated next generation sequencing panel for routine glioma diagnostics

Nathalie Synhaeve (6005657)
Martin van den Bent (3487037)
Pim French (3487031)
Winand Dinjens (6005660)
Peggy Atmodimedjo (6005663)
Johan Kros (3629321)
R. Verdijk (6005666)
Clemens Dirven (568812)
Hendrikus Dubbink (6005669)

November 2018

Figure S2a-c. A 38âyear old female presented with burn-out complaints and several episodes suggest...

Additional file 6: of PIK3CA activating mutations are associated with more disseminated disease at presentation and earlier recurrence in glioblastoma

Abstract

Extracted data

Additional file 6: of PIK3CA activating mutations are associated with more disseminated disease at presentation and earlier recurrence in glioblastoma

Abstract

Extracted data

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