Amifostine showed an inhibition effect on the differentiation of Raw264.7 cells to osteoclasts under 2Gy radiation by reducing ROS

Normal tissue radioprotection by amifostine via Warburg-type effects.

Koukourakis, MI
Giatromanolaki, A
Zois, CE
Kalamida, D
Pouliliou, S
Karagounis, IV
Yeh, T-L
Abboud, MI
Claridge, T
Schofield, C
Sivridis, E
Simopoulos, C
Tokmakidis, SP
Harris, A

August 2016

The mechanism of Amifostine (WR-2721) mediated radioprotection is poorly understood. The effects of ...

ON01210.Na protects human bone marrow cells from radiation exposure.

Anthony D. Kang (386819)
Stephen C. Cosenza (386820)
Marie Bonagura (386821)
Manoj Manair (386822)
M. V. Ramana Reddy (386823)
E. Premkumar Reddy (386824)

March 2013

Human bone marrow cells were pre-treated with varying concentrations of ON01210.Na (A) or Amifost...

Amifostine Increases FAS and Caspase-3 Expression in Colonic Tissue of Irradiated Mice

Oshima, Celina Tizuko Fujiyama
Ribeiro, Daniel Araki
Gomes, Thiago Simao
Adios, Priscila C.
Egami, Mizue Imoto
Segreto, Helena Regina Comodo

May 2015

Background/Aim: The aim of this study was to evaluate the expression of FASL, FAS and FADD and caspa...

Amifostine reduces the effect of radiation on BMSCSs by promoting cell proliferation and reducing ROS

Bo Huang (5231489)
Tao He (23919)
Qianqian Yao (753723)
Liang Zhang (41392)
Hua Tang (1264)
Ping Gong (37151)

July 2018

The figure and the raw data of the article"Amifostine reduces the effect of radiati...

Amifostine Suppresses the Side Effects of Radiation on BMSCs by Promoting Cell Proliferation and Reducing ROS Production

Bo Huang
Tao He
Qianqian Yao
Liang Zhang
Yang Yao
Hua Tang
Ping Gong

January 2019

This study is aimed at investigating the effect of amifostine (AMI) on rat bone marrow stromal stem ...

Amifostine does not prevent activation of TGF beta 1 but induces smad 7 activation in megakaryocytes irradiated in vivo

Segreto, HRC
Ferreira, A. T.
Kimura, E. T.
Franco, M.
Egami, M. I.
Silva, MRR
Segreto, R. A.

November 2002

Experiments were undertaken to assess the role of amifostine in the activation of latent TGFbeta1 an...

Amifostine Does Not Prevent Activation of TGF1 but Induces smad 7 Activation in Megakaryocytes Irradiated

In Vivo
Maria Regina
R. Silva
Roberto A. Segreto

October 2016

Experiments were undertaken to assess the role of amifostine in the activation of latent TGF1 and in...

The effect of amifostine on differentiation of the human megakaryoblastic Dami cell line

Wang, Hai-tao
Yang, Bo
Hu, Bo
Chi, Xiao-hua
Luo, Long-long
Yang, Hong-qi
Lang, Xiao-ling
Geng, Jing
Qiao, Chun-xia
Li, Yan
Wu, Xiao-Xiong
Zhu, Hong-li
Lv, Ming
Lu, Xue-chun

January 2016

Amifostine is a cytoprotective drug that was initially used to control and treat nuclear radiation i...

Protection from radiation-induced apoptosis by the radioprotector amifostine (WR-2721) is radiation dose dependent

Ormsby, R.
Lawrence, M.
Blyth, B.
Bexis, K.
Bezak, E.
Murley, J.
Grdina, D.
Sykes, P.

January 2014

The radioprotective agent amifostine is a free radical scavenger that can protect cells from the dam...

Radiation-induced craniofacial bone growth inhibition: in vitro cytoprotection in the rabbit orbitozygomatic complex periosteum-derived cell culture

Gevorgyan, Artur M.
La Scala, Giorgio
Sukhu, Balram
Leung, Iona T.
Ashrafpour, Homa
Yeung, Ivan
Neligan, Peter C.
Pang, Cho Y.
Forrest, Christopher R.

January 2008

BACKGROUND: Radiotherapy for the management of head and neck cancer in pediatric patients results in...

Radioprotection of craniofacial bone growth

Gevorgyan, Artur
La Scala, Giorgio
Neligan, Peter C
Pang, Cho Y
Forrest, Christopher R

January 2007

In this review, the potential of pharmacologic therapy for prevention of radiation-induced bone grow...

Evaluation of the role of mannitol in radioprotection of amifostine

M. R. Abbasi
M. Foroughizadeh Moghaddam
H. Mozdarani

September 2016

Background: Mannitol is present in the Ethyol ® (the trade name of amifostine) as an excipient. The ...

Amifostine protects mouse liver against radiation-induced autophagy blockage

Koukourakis, M
Giatromanolaki, A
Fylaktakidou, K
Kouroupi, M
Sivridis, E
Zois, C
Kalamida, D
Mitrakas, A
Pouliliou, S
Karagounis, I
Simopoulos, K
Ferguson, D
Harris, A

January 2018

Background/Aim: Amifostine is the only selective normal tissue cytoprotector, approved for the prote...

Research Article SOD2 Mediates Amifostine-Induced Protection against

Glutamate In Pc Cells
Xiaonan Liu
Tingting Huo

August 2016

permits unrestricted use, distribution, and reproduction in any medium, provided the original work i...

The bone marrow cells radioprotection by amifostine - NN/N ratio, apoptosis, ultrastructural and lipid matrix evaluation

Segreto, Roberto Araujo
Egami, Mizue Imoto
França, Jerônimo Pereira de
Silva, MRR
Ferreira, Alice Teixeira
Segreto, Helena Regina Comodo

April 1999

The present experiment was performed in order to estimate the amifostine-WR2721 (ami) bone marrow ce...

Normal tissue radioprotection by amifostine via Warburg-type effects.

Koukourakis, MI
Giatromanolaki, A
Zois, CE
Kalamida, D
Pouliliou, S
Karagounis, IV
Yeh, T-L
Abboud, MI
Claridge, T
Schofield, C
Sivridis, E
Simopoulos, C
Tokmakidis, SP
Harris, A

August 2016

The mechanism of Amifostine (WR-2721) mediated radioprotection is poorly understood. The effects of ...

ON01210.Na protects human bone marrow cells from radiation exposure.

Anthony D. Kang (386819)
Stephen C. Cosenza (386820)
Marie Bonagura (386821)
Manoj Manair (386822)
M. V. Ramana Reddy (386823)
E. Premkumar Reddy (386824)

March 2013

Human bone marrow cells were pre-treated with varying concentrations of ON01210.Na (A) or Amifost...

Amifostine Increases FAS and Caspase-3 Expression in Colonic Tissue of Irradiated Mice

Oshima, Celina Tizuko Fujiyama
Ribeiro, Daniel Araki
Gomes, Thiago Simao
Adios, Priscila C.
Egami, Mizue Imoto
Segreto, Helena Regina Comodo

May 2015

Background/Aim: The aim of this study was to evaluate the expression of FASL, FAS and FADD and caspa...

Amifostine reduces the effect of radiation on BMSCSs by promoting cell proliferation and reducing ROS

Bo Huang (5231489)
Tao He (23919)
Qianqian Yao (753723)
Liang Zhang (41392)
Hua Tang (1264)
Ping Gong (37151)

July 2018

The figure and the raw data of the article"Amifostine reduces the effect of radiati...

Amifostine Suppresses the Side Effects of Radiation on BMSCs by Promoting Cell Proliferation and Reducing ROS Production

Bo Huang
Tao He
Qianqian Yao
Liang Zhang
Yang Yao
Hua Tang
Ping Gong

January 2019

This study is aimed at investigating the effect of amifostine (AMI) on rat bone marrow stromal stem ...

Amifostine does not prevent activation of TGF beta 1 but induces smad 7 activation in megakaryocytes irradiated in vivo

Segreto, HRC
Ferreira, A. T.
Kimura, E. T.
Franco, M.
Egami, M. I.
Silva, MRR
Segreto, R. A.

November 2002

Experiments were undertaken to assess the role of amifostine in the activation of latent TGFbeta1 an...

Amifostine Does Not Prevent Activation of TGF1 but Induces smad 7 Activation in Megakaryocytes Irradiated

In Vivo
Maria Regina
R. Silva
Roberto A. Segreto

October 2016

Experiments were undertaken to assess the role of amifostine in the activation of latent TGF1 and in...

The effect of amifostine on differentiation of the human megakaryoblastic Dami cell line

Wang, Hai-tao
Yang, Bo
Hu, Bo
Chi, Xiao-hua
Luo, Long-long
Yang, Hong-qi
Lang, Xiao-ling
Geng, Jing
Qiao, Chun-xia
Li, Yan
Wu, Xiao-Xiong
Zhu, Hong-li
Lv, Ming
Lu, Xue-chun

January 2016

Amifostine is a cytoprotective drug that was initially used to control and treat nuclear radiation i...

Protection from radiation-induced apoptosis by the radioprotector amifostine (WR-2721) is radiation dose dependent

Ormsby, R.
Lawrence, M.
Blyth, B.
Bexis, K.
Bezak, E.
Murley, J.
Grdina, D.
Sykes, P.

January 2014

The radioprotective agent amifostine is a free radical scavenger that can protect cells from the dam...

Radiation-induced craniofacial bone growth inhibition: in vitro cytoprotection in the rabbit orbitozygomatic complex periosteum-derived cell culture

Gevorgyan, Artur M.
La Scala, Giorgio
Sukhu, Balram
Leung, Iona T.
Ashrafpour, Homa
Yeung, Ivan
Neligan, Peter C.
Pang, Cho Y.
Forrest, Christopher R.

January 2008

BACKGROUND: Radiotherapy for the management of head and neck cancer in pediatric patients results in...

Radioprotection of craniofacial bone growth

Gevorgyan, Artur
La Scala, Giorgio
Neligan, Peter C
Pang, Cho Y
Forrest, Christopher R

January 2007

In this review, the potential of pharmacologic therapy for prevention of radiation-induced bone grow...

Evaluation of the role of mannitol in radioprotection of amifostine

M. R. Abbasi
M. Foroughizadeh Moghaddam
H. Mozdarani

September 2016

Background: Mannitol is present in the Ethyol ® (the trade name of amifostine) as an excipient. The ...

Amifostine protects mouse liver against radiation-induced autophagy blockage

Koukourakis, M
Giatromanolaki, A
Fylaktakidou, K
Kouroupi, M
Sivridis, E
Zois, C
Kalamida, D
Mitrakas, A
Pouliliou, S
Karagounis, I
Simopoulos, K
Ferguson, D
Harris, A

January 2018

Background/Aim: Amifostine is the only selective normal tissue cytoprotector, approved for the prote...

Research Article SOD2 Mediates Amifostine-Induced Protection against

Glutamate In Pc Cells
Xiaonan Liu
Tingting Huo

August 2016

permits unrestricted use, distribution, and reproduction in any medium, provided the original work i...

The bone marrow cells radioprotection by amifostine - NN/N ratio, apoptosis, ultrastructural and lipid matrix evaluation

Segreto, Roberto Araujo
Egami, Mizue Imoto
França, Jerônimo Pereira de
Silva, MRR
Ferreira, Alice Teixeira
Segreto, Helena Regina Comodo

April 1999

The present experiment was performed in order to estimate the amifostine-WR2721 (ami) bone marrow ce...

Normal tissue radioprotection by amifostine via Warburg-type effects.

Koukourakis, MI
Giatromanolaki, A
Zois, CE
Kalamida, D
Pouliliou, S
Karagounis, IV
Yeh, T-L
Abboud, MI
Claridge, T
Schofield, C
Sivridis, E
Simopoulos, C
Tokmakidis, SP
Harris, A

August 2016

The mechanism of Amifostine (WR-2721) mediated radioprotection is poorly understood. The effects of ...

ON01210.Na protects human bone marrow cells from radiation exposure.

Anthony D. Kang (386819)
Stephen C. Cosenza (386820)
Marie Bonagura (386821)
Manoj Manair (386822)
M. V. Ramana Reddy (386823)
E. Premkumar Reddy (386824)

March 2013

Human bone marrow cells were pre-treated with varying concentrations of ON01210.Na (A) or Amifost...

Amifostine Increases FAS and Caspase-3 Expression in Colonic Tissue of Irradiated Mice

Oshima, Celina Tizuko Fujiyama
Ribeiro, Daniel Araki
Gomes, Thiago Simao
Adios, Priscila C.
Egami, Mizue Imoto
Segreto, Helena Regina Comodo

May 2015

Background/Aim: The aim of this study was to evaluate the expression of FASL, FAS and FADD and caspa...

Amifostine showed an inhibition effect on the differentiation of Raw264.7 cells to osteoclasts under 2Gy radiation by reducing ROS

Abstract

Extracted data

Amifostine showed an inhibition effect on the differentiation of Raw264.7 cells to osteoclasts under 2Gy radiation by reducing ROS

Abstract

Extracted data

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