Finding driver mutations in cancer: Elucidating the role of background mutational processes - Fig 1

Mutability of all theoretically possible codon substitutions (“not observed”) and all substitutions that were observed in: (A) COSMIC v85 pan-cancer cohort; (B) MSK-IMPACT cohort. Asterisks show the differences on Mann-Whitney-Wilcoxon test significant at p 10 scale as pan-cancer codon mutability ranges several orders of magnitude.