Figure S4. PCR analysis. Two oligos flanking the deleted regions were used to amplify the genomic DNA from several mutant representative HEK293 and SK-N-MC clones. Black triangles show the size of the PCR products. Black or white asterisks show respectively the clones harbouring a homozygous or heterozygous deletion included in this study. M: molecular weight marker, WT/WT: wild type, Δ/Δ: homozygous deletion, WT/Δ: heterozygous deletion. (JPG 1181 kb
Figure S13. Unexpected outcome of CRISPR/Cas9-aided mutagenesis. The figure illustrates an example o...
H3K9me3 spreading in kmt2/∆set-1 strain. Heatmap display signal distribution for (A) H3K9me3 (B) H4K...
Figure S5. Scatter plot of OCI-AML3 chr 13 showing medial q-arm deletion and possible small distal d...
Figure S1. Genomic map of FOXP2 and MDFIC region. A. Chromosome 7 ideogram representation. Red box s...
Restriction maps of Skt/Etl4 alleles. Schematic representation of the relevant regions of various Sk...
Insertion of triple poly (A) into exon 5 of the Skt/Etl4 does not prevent transcription of downstrea...
Figure S1. Screening by Sanger sequencing of animals for the generation of a Syt7 conditional allele...
Figure S1. a–c The distribution of Tajima’s D for DNase footprint SNPs in each subpopulation. d Over...
Figure S4. Analysis of the Ikzf2 project. PCR amplification of the genomic region of interest from (...
Figure S5. Analysis of the Syt4 project. PCR amplification of the genomic region of interest with (a...
Figure S6. Detailed view of an ENCODE UCSC genome-browser snapshot showing bar graphs with a detaile...
Figure S6. Analysis of the Usp45 project. The figure shows the PCR amplification of the genomic regi...
Figure S2. Indel spectrum determined by TIDE of the on-target sites compared with indel frequencies ...
Figure S1. Analysis of H3K4me1 and H3K27ac modifications on the 13q-Enh using ChIP assays in Beas-2B...
Analysis of enhancer regions based on CpG islands. Distribution of the H3K4me3, H3K27me3, bivalent a...
Figure S13. Unexpected outcome of CRISPR/Cas9-aided mutagenesis. The figure illustrates an example o...
H3K9me3 spreading in kmt2/∆set-1 strain. Heatmap display signal distribution for (A) H3K9me3 (B) H4K...
Figure S5. Scatter plot of OCI-AML3 chr 13 showing medial q-arm deletion and possible small distal d...
Figure S1. Genomic map of FOXP2 and MDFIC region. A. Chromosome 7 ideogram representation. Red box s...
Restriction maps of Skt/Etl4 alleles. Schematic representation of the relevant regions of various Sk...
Insertion of triple poly (A) into exon 5 of the Skt/Etl4 does not prevent transcription of downstrea...
Figure S1. Screening by Sanger sequencing of animals for the generation of a Syt7 conditional allele...
Figure S1. a–c The distribution of Tajima’s D for DNase footprint SNPs in each subpopulation. d Over...
Figure S4. Analysis of the Ikzf2 project. PCR amplification of the genomic region of interest from (...
Figure S5. Analysis of the Syt4 project. PCR amplification of the genomic region of interest with (a...
Figure S6. Detailed view of an ENCODE UCSC genome-browser snapshot showing bar graphs with a detaile...
Figure S6. Analysis of the Usp45 project. The figure shows the PCR amplification of the genomic regi...
Figure S2. Indel spectrum determined by TIDE of the on-target sites compared with indel frequencies ...
Figure S1. Analysis of H3K4me1 and H3K27ac modifications on the 13q-Enh using ChIP assays in Beas-2B...
Analysis of enhancer regions based on CpG islands. Distribution of the H3K4me3, H3K27me3, bivalent a...
Figure S13. Unexpected outcome of CRISPR/Cas9-aided mutagenesis. The figure illustrates an example o...
H3K9me3 spreading in kmt2/∆set-1 strain. Heatmap display signal distribution for (A) H3K9me3 (B) H4K...
Figure S5. Scatter plot of OCI-AML3 chr 13 showing medial q-arm deletion and possible small distal d...