Purpose: To study which brain volume measures best differentiate early relapsing MS (RMS) and secondary progressive MS (SPMS) patients and correlate with disability and cognition. To test whether isolated thalamic atrophy at study baseline correlates with NEDA (no evidence of disease activity) at 2 years.Methods: Total and regional brain volumes were measured from 24 newly diagnosed RMS patients 6 months after initiation of therapy and 2 years thereafter, and in 36 SPMS patients. Volumes were measured by SIENAX and cNeuro. The patients were divided into subgroups based on whole brain parenchyma (BP) and thalamic atrophy at baseline. Standard scores (z-scores) were computed by comparing individual brain volumes against healthy controls. A z-...
OBJECTIVE: To determine the relation of gray matter (GM) and white matter (WM) brain volumes, and WM...
Background: 'No evidence of disease activity' (NEDA), defined as absence of magnetic resonance imagi...
Objective: To investigate the relationship between brain volume and disability worsening over ≥3 yea...
Purpose: To study which brain volume measures best differentiate early relapsing MS (RMS) and second...
Purpose: To study which brain volume measures best differentiate early relapsing MS (RMS) and second...
<p>Purpose: Thalamic atrophy and whole brain atrophy in multiple sclerosis (MS) are associated with ...
Purpose:Thalamus is among the first brain regions to become atrophic in multiple sclerosis (MS). We ...
Purpose: Thalamic atrophy and whole brain atrophy in multiple sclerosis (MS) are associated with dis...
Background: In multiple sclerosis (MS), brain atrophy depicted by magnetic resonance imaging reflect...
The concept of no evidence of disease activity (NEDA) has emerged as an important outcome measure fo...
Aims: The objective of the study was to assess whether changes in the volume of the thalamus during ...
OBJECTIVE: To assess the time course of brain atrophy and the difference across clinical subtypes in...
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Coordenação de Aperfeiçoamento de Pesso...
Background'No evidence of disease activity' (NEDA), defined as absence of magnetic resonance imaging...
OBJECTIVE: To determine whether brain atrophy and lesion volumes predict subsequent 10 year clinica...
OBJECTIVE: To determine the relation of gray matter (GM) and white matter (WM) brain volumes, and WM...
Background: 'No evidence of disease activity' (NEDA), defined as absence of magnetic resonance imagi...
Objective: To investigate the relationship between brain volume and disability worsening over ≥3 yea...
Purpose: To study which brain volume measures best differentiate early relapsing MS (RMS) and second...
Purpose: To study which brain volume measures best differentiate early relapsing MS (RMS) and second...
<p>Purpose: Thalamic atrophy and whole brain atrophy in multiple sclerosis (MS) are associated with ...
Purpose:Thalamus is among the first brain regions to become atrophic in multiple sclerosis (MS). We ...
Purpose: Thalamic atrophy and whole brain atrophy in multiple sclerosis (MS) are associated with dis...
Background: In multiple sclerosis (MS), brain atrophy depicted by magnetic resonance imaging reflect...
The concept of no evidence of disease activity (NEDA) has emerged as an important outcome measure fo...
Aims: The objective of the study was to assess whether changes in the volume of the thalamus during ...
OBJECTIVE: To assess the time course of brain atrophy and the difference across clinical subtypes in...
Fundação de Amparo à Pesquisa do Estado de São Paulo (FAPESP)Coordenação de Aperfeiçoamento de Pesso...
Background'No evidence of disease activity' (NEDA), defined as absence of magnetic resonance imaging...
OBJECTIVE: To determine whether brain atrophy and lesion volumes predict subsequent 10 year clinica...
OBJECTIVE: To determine the relation of gray matter (GM) and white matter (WM) brain volumes, and WM...
Background: 'No evidence of disease activity' (NEDA), defined as absence of magnetic resonance imagi...
Objective: To investigate the relationship between brain volume and disability worsening over ≥3 yea...