Functional analysis of disease-associated genes.

Functional analysis summary for 7 out of 8 disease-associated gene clusters. The top functional terms from Gene Ontology (GO), KEGG Pathways and Transcription Factor binding sites (TRANSFAC) are reported separately for (A) over- and (B) under-expressed (right) gene clusters. Values are reported as -log10(p-value) of enrichment on the basis of a hypergeometric test, adjusted for an FDR of 95%. gProfiler was used for all levels of functional enrichment analysis.