Allergen-induced airway inflammation.

Lung tissues were obtained on Day 50 from the mice of PBS, OVA, HBoV-VP1u and B19V-VP1u groups. (A) MMP-9 and MMP-2 activity were detected by gelatin zymography. Quantified results of MMP-9 and MMP-2 activities were shown in the lower panel. (B) The sections of lung tissues were stained with hematoxylin and eosin and revealed with a magnification ratio of 1:100 (upper panel) or 1:400 (lower panel). Amplified images were shown in the lower panel of each section. The lymphocyte infiltration was indicated by an arrow. Values are mean ± SD. Similar results were observed in three repeated experiments. * and & indicate significant difference, p<0.05, relative to PBS and OVA groups, respectively. (n = 5 for each group).