Additional file 1: of The frailty index is a predictor of cause-specific mortality independent of familial effects from midlife onwards: a large cohort study

Table S1. Grouping of the study population. Table S2. The 44 frailty items and the coding rules. Table S3. ICD codes used to classify the cause-specific mortality. Table S4. Consensus classification for the cause-specific mortality when more than one cause of death was recorded. Table S5. Time-constant associations between 10% increase in the FI and all-cause and cause-specific mortality. Table S6. Assessment of time-dependent associations between FI and mortality in single responders. Table S7. Sensitivity analyses on the associations between 10% FI increase on all-cause and cause-specific mortality in single responders. Table S8. Generalized attributable fractions (%, 95%CI) for all-cause and cause-specific mortality in single responders at the attained age of 80. Table S9. Generalized attributable fractions (%, 95%CI) for all-cause and cause-specific mortality in twins at the attained age of 80. Figure S1. Distribution of the frailty index in our sample. Appendix S1 Imputation of missing values. Appendix S2 Specification of generalized survival models (GSM) fitted to the data. (DOCX 66 kb