Molecular annotation of external cohort in function of TNBC clusters and non-TNBC. Radar plot showing the segregation of three clusters as a function of 47 continuous score GES. This figure is an illustration of Additional file 26. Each of the 47 radii represents a GES. Black circles represent significantly different levels of expression from low (smallest circle) to high (largest circle). Expression level of each cluster is represented on the corresponding circle as a dark gray (NTN), blue (C’1), red (C’2) or green (C’3) dot. Dots located on same circles correspond to clusters with not significantly different expressions. Dots located on different circles correspond to clusters with significantly different expressions. Dots located in betw...
Biological gradients between C2 and C3 in our internal cohort. Correlation coefficient calculation b...
Expression of immune checkpoints between basal-like clusters. Internal (C2 vs C3) and external (C’2 ...
Projection of internal TNBC cohort in the first PCA plane. (C1, n = 55 [blue]; C2, n = 98 [red]; C3,...
Continuous score GES analyses results in function of external TNBC (C’1, C’2, C’3) and non-TNBC clus...
Continuous score GES analyses results in function of external TNBC clusters (C’1, C’2, and C’3). (PD...
Categorical GES analyses interpretation in function of external TNBC (C’1, C’2, C’3) and non-TNBC cl...
Categorical GES analyses result in function of external TNBC clusters (C’1, C’2 and C’3). (PDF 159 k...
Continuous score GES analyses result in function of internal TNBC clusters (C1, C2, and C3). (PDF 17...
Comparison of clinicopathologic characteristics of TNBC cohorts in function of clusters. Internal (C...
Categorical GES analyses result in function of internal TNBC clusters (C1, C2, and C3). (PDF 107 kb
External TNBC cohort’s clinicopathologic characteristics in function of the three clusters (C’1, C’2...
Projection of internal TNBC cohorts in the first PCA plane. (A) PACS08 patients (n = 131, [orange]) ...
PCA result representation of external TNBC and non-TNBC data. PCA is computed based on the TNBC data...
ToppGene GOEA based on heatmap gene clusters, internal cohort (1843 probes) and external cohorts (45...
Fuzzy clustering of 238 TNBC. Distribution of patients based on probability of belonging to cluster:...
Biological gradients between C2 and C3 in our internal cohort. Correlation coefficient calculation b...
Expression of immune checkpoints between basal-like clusters. Internal (C2 vs C3) and external (C’2 ...
Projection of internal TNBC cohort in the first PCA plane. (C1, n = 55 [blue]; C2, n = 98 [red]; C3,...
Continuous score GES analyses results in function of external TNBC (C’1, C’2, C’3) and non-TNBC clus...
Continuous score GES analyses results in function of external TNBC clusters (C’1, C’2, and C’3). (PD...
Categorical GES analyses interpretation in function of external TNBC (C’1, C’2, C’3) and non-TNBC cl...
Categorical GES analyses result in function of external TNBC clusters (C’1, C’2 and C’3). (PDF 159 k...
Continuous score GES analyses result in function of internal TNBC clusters (C1, C2, and C3). (PDF 17...
Comparison of clinicopathologic characteristics of TNBC cohorts in function of clusters. Internal (C...
Categorical GES analyses result in function of internal TNBC clusters (C1, C2, and C3). (PDF 107 kb
External TNBC cohort’s clinicopathologic characteristics in function of the three clusters (C’1, C’2...
Projection of internal TNBC cohorts in the first PCA plane. (A) PACS08 patients (n = 131, [orange]) ...
PCA result representation of external TNBC and non-TNBC data. PCA is computed based on the TNBC data...
ToppGene GOEA based on heatmap gene clusters, internal cohort (1843 probes) and external cohorts (45...
Fuzzy clustering of 238 TNBC. Distribution of patients based on probability of belonging to cluster:...
Biological gradients between C2 and C3 in our internal cohort. Correlation coefficient calculation b...
Expression of immune checkpoints between basal-like clusters. Internal (C2 vs C3) and external (C’2 ...
Projection of internal TNBC cohort in the first PCA plane. (C1, n = 55 [blue]; C2, n = 98 [red]; C3,...