Number of animals required per group to obtain 80% power with a significance level of 0.05 using mechanical monofilaments, Randall-Selitto paw pressure test, electronic ‘von Frey’, acetone test/ethyl chloride spray, cold plate, and Hargreave’s. Effect sizes calculated by SMD. SMD, standardised mean difference.</p
We estimated the statistical power of the first and last statistical test presented in 697 papers fr...
What is the optimal size of an experiment? How should the practical experimenter determine this opti...
<p>Power of mouse meta-analysis to identify gene-by-environment interactions in 4,965 animals from 1...
Animal models are widely used in the field of nutrition research. Scientifically and ethically sound...
<p>Plot illustrating the statistical power calculations for the study assuming four (two animals per...
<p>The mixed model methodology sensitivity was assessed with a resampling study on simulated control...
<p><b>A</b> Power estimates are shown as a function of the effect size measured by the variance para...
<p>Power estimates are shown as a function of the effect size. The <i>in silico</i> challenge data a...
The power was calculated as 0.9963 based on the anticipated effect size of SMD = 0.8, the 10 identif...
The use of model‐based drug development (MBDD) has been demonstrated to improve the efficiency of cl...
<p>A) Power as a function of contamination proportion. B) Power as a function of study size. C) Powe...
Overview of the studies used for model building (A-F) and external evaluation (G), including a short...
Key Words: animal experiments; experimental design; sample size; statistics; variation esearch scien...
A. Schema of factors influencing model complexity and affected facets of model performance. Dashed o...
Thigmotactic effect sizes associated with the reporting of the six methodological quality criteria i...
We estimated the statistical power of the first and last statistical test presented in 697 papers fr...
What is the optimal size of an experiment? How should the practical experimenter determine this opti...
<p>Power of mouse meta-analysis to identify gene-by-environment interactions in 4,965 animals from 1...
Animal models are widely used in the field of nutrition research. Scientifically and ethically sound...
<p>Plot illustrating the statistical power calculations for the study assuming four (two animals per...
<p>The mixed model methodology sensitivity was assessed with a resampling study on simulated control...
<p><b>A</b> Power estimates are shown as a function of the effect size measured by the variance para...
<p>Power estimates are shown as a function of the effect size. The <i>in silico</i> challenge data a...
The power was calculated as 0.9963 based on the anticipated effect size of SMD = 0.8, the 10 identif...
The use of model‐based drug development (MBDD) has been demonstrated to improve the efficiency of cl...
<p>A) Power as a function of contamination proportion. B) Power as a function of study size. C) Powe...
Overview of the studies used for model building (A-F) and external evaluation (G), including a short...
Key Words: animal experiments; experimental design; sample size; statistics; variation esearch scien...
A. Schema of factors influencing model complexity and affected facets of model performance. Dashed o...
Thigmotactic effect sizes associated with the reporting of the six methodological quality criteria i...
We estimated the statistical power of the first and last statistical test presented in 697 papers fr...
What is the optimal size of an experiment? How should the practical experimenter determine this opti...
<p>Power of mouse meta-analysis to identify gene-by-environment interactions in 4,965 animals from 1...