(A,B) Representative western blots for MBNL1 and MBNL2 from cell lines with (4F9-13/2600) and without (4A3-ΔΔ) the (CTG)2600 repeat. (C,D) Quantification of MBNL1 and MBNL2 expression, including specific variants, in arbitrary units (a.u.) after normalization to β-tubulin expression. Bars summarize data from two cell lines with and two cell lines without (CTG)2600 repeat. Each cell line was measured three times, in independent experiments.</p
<p>(<b>a</b>) Left: Concentration response curve for <i>BCL2</i> RNA expression following 24 hour tr...
<p>(<b>A</b>) Schematic depicting <i>Msl2</i> locus and targeting strategy: A targeting cassette wit...
<p>(<b>A</b>) Representative immunoblot analysis of nuclear extracts prepared from wild-type, <i>Msl...
(A) Schematic outline of the CRISPR/Cas9 editing procedure by which the (CTG)2600 repeat was excised...
(A, B) Gene structures of MBNL1 and MBNL2, adapted from [1,11]. Boxes represent exons, numbered 1–10...
(A, B) Immunofluorescent localization of MBNL1 and MBNL2 in proliferating myoblasts with (4F9) and w...
(A-D) Immunofluorescent localization of MBNL1 and MBNL2 in myotubes with (4F9) and without (4A3) the...
(A) Western blot for SETD2, H3K36me3, H3, and FMRP in nuclear extracts of control and Fmr1-deficient...
<p><b><i>A.</i></b> RT-qPCR showing the mRNA expression levels of <i>MSLN</i> measured on MPM cell l...
Contains fulltext : 203961.pdf (publisher's version ) (Open Access
<p><b>A)</b> INDEL analysis of MnlI-TALEN and NcoI-TALEN N-Muli treated cells. The left and right ar...
<p>A. Western blot of the DM1 human myoblasts transfected with various EGFP-MBNL1 fusion constructs ...
<p><b>A</b>: Liver, <b>B</b>: Epididymal White adipose, <b>C</b>: Isolated islets, <b>D</b>: Skeleta...
<p>(A) Overlap in gene expression changes between MA1 and MA2 variants. The Venn diagram depicts the...
<p>A) qRT-PCR and B) Western blot analysis was performed to assess the expression of oncogenes in U-...
<p>(<b>a</b>) Left: Concentration response curve for <i>BCL2</i> RNA expression following 24 hour tr...
<p>(<b>A</b>) Schematic depicting <i>Msl2</i> locus and targeting strategy: A targeting cassette wit...
<p>(<b>A</b>) Representative immunoblot analysis of nuclear extracts prepared from wild-type, <i>Msl...
(A) Schematic outline of the CRISPR/Cas9 editing procedure by which the (CTG)2600 repeat was excised...
(A, B) Gene structures of MBNL1 and MBNL2, adapted from [1,11]. Boxes represent exons, numbered 1–10...
(A, B) Immunofluorescent localization of MBNL1 and MBNL2 in proliferating myoblasts with (4F9) and w...
(A-D) Immunofluorescent localization of MBNL1 and MBNL2 in myotubes with (4F9) and without (4A3) the...
(A) Western blot for SETD2, H3K36me3, H3, and FMRP in nuclear extracts of control and Fmr1-deficient...
<p><b><i>A.</i></b> RT-qPCR showing the mRNA expression levels of <i>MSLN</i> measured on MPM cell l...
Contains fulltext : 203961.pdf (publisher's version ) (Open Access
<p><b>A)</b> INDEL analysis of MnlI-TALEN and NcoI-TALEN N-Muli treated cells. The left and right ar...
<p>A. Western blot of the DM1 human myoblasts transfected with various EGFP-MBNL1 fusion constructs ...
<p><b>A</b>: Liver, <b>B</b>: Epididymal White adipose, <b>C</b>: Isolated islets, <b>D</b>: Skeleta...
<p>(A) Overlap in gene expression changes between MA1 and MA2 variants. The Venn diagram depicts the...
<p>A) qRT-PCR and B) Western blot analysis was performed to assess the expression of oncogenes in U-...
<p>(<b>a</b>) Left: Concentration response curve for <i>BCL2</i> RNA expression following 24 hour tr...
<p>(<b>A</b>) Schematic depicting <i>Msl2</i> locus and targeting strategy: A targeting cassette wit...
<p>(<b>A</b>) Representative immunoblot analysis of nuclear extracts prepared from wild-type, <i>Msl...