MOESM1 of Enhancement of tanshinone production in Salvia miltiorrhiza hairy root cultures by metabolic engineering

Cloning and characterization of a novel 3-hydroxy-3-methylglutaryl coenzyme A reductase gene from salvia miltiorrhiza involved in diterpenoid tanshinone accumulation

Zhubo, D
guanghong, C
Zhou, S
Xianan, Z
Huang, L

January 2010

The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) catalyzes the conversion of HMG-CoA to mevalonat...

Effects of Combined Elicitors on Tanshinone Metabolic Profiling and SmCPS Expression in Salvia miltiorrhiza Hairy Root Cultures

Qiqing Cheng

June 2013

Tanshinones are abietane-type norditerpenoid quinone natural products found in a well-known traditio...

Effects of Combined Elicitors on Tanshinone Metabolic Profiling and SmCPS Expression in Salvia miltiorrhiza Hairy Root Cultures

Yujia Liu
Wei Gao
Geng Li
Yunfei He
Qiqing Cheng
Luqi Huang

June 2013

Tanshinones are abietane-type norditerpenoid quinone natural products found in a well-known traditio...

MOESM3 of Enhancement of tanshinone production in Salvia miltiorrhiza hairy root cultures by metabolic engineering

Tao Wei (18855)
Yonghong Gao (6279332)
Kejun Deng (694852)
Lipeng Zhang (138745)
Meiling Yang (153319)
Xiaopei Liu (5673878)
Caiyan Qi (6731228)
Chunguo Wang (500179)
Wenqin Song (5626007)
Yong Zhang (5893)
Chengbin Chen (5626004)

May 2019

Additional file 3: Figure S3. WT hairy roots on the selective medium (50Â mg/L Kan) at 6 d

MOESM2 of Enhancement of tanshinone production in Salvia miltiorrhiza hairy root cultures by metabolic engineering

Tao Wei (18855)
Yonghong Gao (6279332)
Kejun Deng (694852)
Lipeng Zhang (138745)
Meiling Yang (153319)
Xiaopei Liu (5673878)
Caiyan Qi (6731228)
Chunguo Wang (500179)
Wenqin Song (5626007)
Yong Zhang (5893)
Chengbin Chen (5626004)

May 2019

Additional file 2: Figure S2. Diagram of the T-DNA region of the binary plasmid used for Agrobacteri...

MOESM4 of Enhancement of tanshinone production in Salvia miltiorrhiza hairy root cultures by metabolic engineering

Tao Wei (18855)
Yonghong Gao (6279332)
Kejun Deng (694852)
Lipeng Zhang (138745)
Meiling Yang (153319)
Xiaopei Liu (5673878)
Caiyan Qi (6731228)
Chunguo Wang (500179)
Wenqin Song (5626007)
Yong Zhang (5893)
Chengbin Chen (5626004)

May 2019

Additional file 4: Figure S4. Morphology of transgenic hairy roots after cultured in liquid media fo...

The Biosynthetic Pathways of Tanshinones and Phenolic Acids in Salvia miltiorrhiza

Xiao-Hui Ma

September 2015

Secondary metabolites from plants play key roles in human medicine and chemical industries. Due to l...

Tanshinone production and isoprenoid pathways in Salvia miltiorrhiza hairy roots induced by Ag + and yeast elicitor

Ge, X
Wu, J

January 2005

This work examined the accumulation of diterpenoid tanshinones and related secondary metabolism path...

Different roles of the mevalonate and methylerythritol phosphate pathways in cell growth and tanshinone production of Salvia miltiorrhiza hairy roots.

Dongfeng Yang
Xuhong Du
Xiao Liang
Ruilian Han
Zongsuo Liang
Yan Liu
Fenghua Liu
Jianjun Zhao

Salvia miltiorrhiza has been widely used in the treatment of coronary heart disease. Tanshinones, a ...

Fig. 1 in Endophytic fungus Cladosporium tenuissimum DF11, an efficient inducer of tanshinone biosynthesis in Salvia miltiorrhiza roots

Chen, Haimin
Chen, Jialing
Qi, Yao
Chu, Siyuan
Ma, Yao
Xu, Linna
Lv, Shiyi
Zhang, Haihua
Yang, Dongfeng
Zhu, Yonghong
Mans, Dennis Ra.
Liang, Zongsuo

February 2022

Fig. 1. The tanshinone biosynthesis pathway in S. miltiorrhiza. AACT: acetyl-CoA C-acetyltransferase...

Transcriptome analysis of medicinal plant Salvia miltiorrhiza and identification of genes related to tanshinone biosynthesis.

Lei Yang
Guohui Ding
Haiyan Lin
Haining Cheng
Yu Kong
Yukun Wei
Xin Fang
Renyi Liu
Lingiian Wang
Xiaoya Chen
Changqing Yang

Salvia miltiorrhiza Bunge, a perennial plant of Lamiaceae, accumulates abietane-type diterpenoids of...

Enhanced Diterpene Tanshinone Accumulation and Bioactivity of Transgenic Salvia miltiorrhiza Hairy Roots by Pathway Engineering

Min Shi (141075)
Xiuqin Luo (1440937)
Guanhua Ju (1440940)
Leilei Li (419900)
Shengxiong Huang (142690)
Tong Zhang (103827)
Huizhong Wang (115600)
Guoyin Kai (1440943)

January 2016

Tanshinones are health-promoting diterpenoids found in Salvia miltiorrhiza and have wide application...

Fig. 6 in Endophytic fungus Cladosporium tenuissimum DF11, an efficient inducer of tanshinone biosynthesis in Salvia miltiorrhiza roots

Chen, Haimin
Chen, Jialing
Qi, Yao
Chu, Siyuan
Ma, Yao
Xu, Linna
Lv, Shiyi
Zhang, Haihua
Yang, Dongfeng
Zhu, Yonghong
Mans, Dennis Ra.
Liang, Zongsuo

February 2022

Fig. 6. The effects of DF11 on the expression of genes encoding for key enzymes of tanshinone biosyn...

Functional Divergence of Diterpene Syntheses in the Medicinal Plant Salvia miltiorrhiza

Cui, Guanghong
Duan, Lixin
Jin, Baolong
Qian, Jun
Xue, Zheyong
Shen, Guoan
Hugh Snyder, John
Song, Jingyuan
Chen, Shilin
Huang, Luqi
Peters, Reuben J.
Qi, Xiaoquan

January 2015

The medicinal plant Salvia miltiorrhiza produces various tanshinone diterpenoids that have pharmacol...

Fig. 3 in Characterization of NAC family genes in Salvia miltiorrhiza and NAC2 potentially involved in the biosynthesis of tanshinones

Zhang, Haihua
Xu, Jinfeng
Chen, Haimin
Jin, Weibo
Liang, Zongsuo

November 2021

Fig. 3. Genetic transformation of Sm-NAC2 in S. miltiorrhiza transgenic roots. a, the mevalonate (MV...

Cloning and characterization of a novel 3-hydroxy-3-methylglutaryl coenzyme A reductase gene from salvia miltiorrhiza involved in diterpenoid tanshinone accumulation

Zhubo, D
guanghong, C
Zhou, S
Xianan, Z
Huang, L

January 2010

The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) catalyzes the conversion of HMG-CoA to mevalonat...

Effects of Combined Elicitors on Tanshinone Metabolic Profiling and SmCPS Expression in Salvia miltiorrhiza Hairy Root Cultures

Qiqing Cheng

June 2013

Tanshinones are abietane-type norditerpenoid quinone natural products found in a well-known traditio...

Effects of Combined Elicitors on Tanshinone Metabolic Profiling and SmCPS Expression in Salvia miltiorrhiza Hairy Root Cultures

Yujia Liu
Wei Gao
Geng Li
Yunfei He
Qiqing Cheng
Luqi Huang

June 2013

Tanshinones are abietane-type norditerpenoid quinone natural products found in a well-known traditio...

MOESM3 of Enhancement of tanshinone production in Salvia miltiorrhiza hairy root cultures by metabolic engineering

Tao Wei (18855)
Yonghong Gao (6279332)
Kejun Deng (694852)
Lipeng Zhang (138745)
Meiling Yang (153319)
Xiaopei Liu (5673878)
Caiyan Qi (6731228)
Chunguo Wang (500179)
Wenqin Song (5626007)
Yong Zhang (5893)
Chengbin Chen (5626004)

May 2019

Additional file 3: Figure S3. WT hairy roots on the selective medium (50Â mg/L Kan) at 6 d

MOESM2 of Enhancement of tanshinone production in Salvia miltiorrhiza hairy root cultures by metabolic engineering

Tao Wei (18855)
Yonghong Gao (6279332)
Kejun Deng (694852)
Lipeng Zhang (138745)
Meiling Yang (153319)
Xiaopei Liu (5673878)
Caiyan Qi (6731228)
Chunguo Wang (500179)
Wenqin Song (5626007)
Yong Zhang (5893)
Chengbin Chen (5626004)

May 2019

Additional file 2: Figure S2. Diagram of the T-DNA region of the binary plasmid used for Agrobacteri...

MOESM4 of Enhancement of tanshinone production in Salvia miltiorrhiza hairy root cultures by metabolic engineering

Tao Wei (18855)
Yonghong Gao (6279332)
Kejun Deng (694852)
Lipeng Zhang (138745)
Meiling Yang (153319)
Xiaopei Liu (5673878)
Caiyan Qi (6731228)
Chunguo Wang (500179)
Wenqin Song (5626007)
Yong Zhang (5893)
Chengbin Chen (5626004)

May 2019

Additional file 4: Figure S4. Morphology of transgenic hairy roots after cultured in liquid media fo...

The Biosynthetic Pathways of Tanshinones and Phenolic Acids in Salvia miltiorrhiza

Xiao-Hui Ma

September 2015

Secondary metabolites from plants play key roles in human medicine and chemical industries. Due to l...

Tanshinone production and isoprenoid pathways in Salvia miltiorrhiza hairy roots induced by Ag + and yeast elicitor

Ge, X
Wu, J

January 2005

This work examined the accumulation of diterpenoid tanshinones and related secondary metabolism path...

Different roles of the mevalonate and methylerythritol phosphate pathways in cell growth and tanshinone production of Salvia miltiorrhiza hairy roots.

Dongfeng Yang
Xuhong Du
Xiao Liang
Ruilian Han
Zongsuo Liang
Yan Liu
Fenghua Liu
Jianjun Zhao

Salvia miltiorrhiza has been widely used in the treatment of coronary heart disease. Tanshinones, a ...

Fig. 1 in Endophytic fungus Cladosporium tenuissimum DF11, an efficient inducer of tanshinone biosynthesis in Salvia miltiorrhiza roots

Chen, Haimin
Chen, Jialing
Qi, Yao
Chu, Siyuan
Ma, Yao
Xu, Linna
Lv, Shiyi
Zhang, Haihua
Yang, Dongfeng
Zhu, Yonghong
Mans, Dennis Ra.
Liang, Zongsuo

February 2022

Fig. 1. The tanshinone biosynthesis pathway in S. miltiorrhiza. AACT: acetyl-CoA C-acetyltransferase...

Transcriptome analysis of medicinal plant Salvia miltiorrhiza and identification of genes related to tanshinone biosynthesis.

Lei Yang
Guohui Ding
Haiyan Lin
Haining Cheng
Yu Kong
Yukun Wei
Xin Fang
Renyi Liu
Lingiian Wang
Xiaoya Chen
Changqing Yang

Salvia miltiorrhiza Bunge, a perennial plant of Lamiaceae, accumulates abietane-type diterpenoids of...

Enhanced Diterpene Tanshinone Accumulation and Bioactivity of Transgenic Salvia miltiorrhiza Hairy Roots by Pathway Engineering

Min Shi (141075)
Xiuqin Luo (1440937)
Guanhua Ju (1440940)
Leilei Li (419900)
Shengxiong Huang (142690)
Tong Zhang (103827)
Huizhong Wang (115600)
Guoyin Kai (1440943)

January 2016

Tanshinones are health-promoting diterpenoids found in Salvia miltiorrhiza and have wide application...

Fig. 6 in Endophytic fungus Cladosporium tenuissimum DF11, an efficient inducer of tanshinone biosynthesis in Salvia miltiorrhiza roots

Chen, Haimin
Chen, Jialing
Qi, Yao
Chu, Siyuan
Ma, Yao
Xu, Linna
Lv, Shiyi
Zhang, Haihua
Yang, Dongfeng
Zhu, Yonghong
Mans, Dennis Ra.
Liang, Zongsuo

February 2022

Fig. 6. The effects of DF11 on the expression of genes encoding for key enzymes of tanshinone biosyn...

Functional Divergence of Diterpene Syntheses in the Medicinal Plant Salvia miltiorrhiza

Cui, Guanghong
Duan, Lixin
Jin, Baolong
Qian, Jun
Xue, Zheyong
Shen, Guoan
Hugh Snyder, John
Song, Jingyuan
Chen, Shilin
Huang, Luqi
Peters, Reuben J.
Qi, Xiaoquan

January 2015

The medicinal plant Salvia miltiorrhiza produces various tanshinone diterpenoids that have pharmacol...

Fig. 3 in Characterization of NAC family genes in Salvia miltiorrhiza and NAC2 potentially involved in the biosynthesis of tanshinones

Zhang, Haihua
Xu, Jinfeng
Chen, Haimin
Jin, Weibo
Liang, Zongsuo

November 2021

Fig. 3. Genetic transformation of Sm-NAC2 in S. miltiorrhiza transgenic roots. a, the mevalonate (MV...

Cloning and characterization of a novel 3-hydroxy-3-methylglutaryl coenzyme A reductase gene from salvia miltiorrhiza involved in diterpenoid tanshinone accumulation

Zhubo, D
guanghong, C
Zhou, S
Xianan, Z
Huang, L

January 2010

The 3-hydroxy-3-methylglutaryl-CoA reductase (HMGR) catalyzes the conversion of HMG-CoA to mevalonat...

Effects of Combined Elicitors on Tanshinone Metabolic Profiling and SmCPS Expression in Salvia miltiorrhiza Hairy Root Cultures

Qiqing Cheng

June 2013

Tanshinones are abietane-type norditerpenoid quinone natural products found in a well-known traditio...

Effects of Combined Elicitors on Tanshinone Metabolic Profiling and SmCPS Expression in Salvia miltiorrhiza Hairy Root Cultures

Yujia Liu
Wei Gao
Geng Li
Yunfei He
Qiqing Cheng
Luqi Huang

June 2013

Tanshinones are abietane-type norditerpenoid quinone natural products found in a well-known traditio...

MOESM1 of Enhancement of tanshinone production in Salvia miltiorrhiza hairy root cultures by metabolic engineering

Abstract

Extracted data

MOESM1 of Enhancement of tanshinone production in Salvia miltiorrhiza hairy root cultures by metabolic engineering

Abstract

Extracted data

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