(A) Three-dimensional structure of the heme domain of the CYP BM3 M11 mutant (without organic ligand in the active site; PDB entry 5E9Z) [16]. (B) Zoom-in on active site showing a water molecule and Cys400 adopting the axial positions at the hexa-coordinated Fe atom in the heme group. The 2D structure of DTT is also depicted.</p
Heme group, His25 and DTT from the 3D structure of DTT binding to rat heme oxygenase (PDB entry 3I9T...
Panels A and B show two discrete binding modes for compound 1a in the active site of CYP3A4 with eit...
<p>(A) Overview of Isd–NEAT domains; the heme molecule and primary/secondary tyrosine residues on th...
(A) Chains B, C, and D are superposed on chain A. For comparison PDB entry 1JPZ (chain A) with the S...
The bacterial Cytochrome P450 (CYP) BM3 (CYP102A1) is one of the most active CYP isoforms. BM3 mutan...
The bacterial Cytochrome P450 (CYP) BM3 (CYP102A1) is one of the most active CYP isoforms. BM3 mutan...
Two novel P450 heme iron ligand sets were generated by directed mutagenesis of the flavocytochrome P...
<p>(Top) Ribbon views of Mt-trHbN, Mt-trHbO, and Cj-trHbP, including the heme-Fe group (red) and the...
<p>(A) shows the H-bonding network between the propionate groups of heme <i>a</i> and the amino acid...
A nine heme group containing cytochrome c isolated from the soluble and membrane fractions of Desulf...
The crystal structure of bovine Complex III (PDB ID: 2A06) is shown on the left side with separate c...
<p>Residues lining the heme distal pocket are indicated (one letter code) and shown in green for the...
<p>(A) The whole complex structure. CYP2B6.1 is shown by ribbon, heme and AM are shown by ball-and-s...
Crystal data, data collection and structure refinement of CYP BM3 M11 mutant in complex with DTT.</p
<p>A) Cartoon representation of the LepHO-C26S-stop structure. B) Arrangement of the most relevant a...
Heme group, His25 and DTT from the 3D structure of DTT binding to rat heme oxygenase (PDB entry 3I9T...
Panels A and B show two discrete binding modes for compound 1a in the active site of CYP3A4 with eit...
<p>(A) Overview of Isd–NEAT domains; the heme molecule and primary/secondary tyrosine residues on th...
(A) Chains B, C, and D are superposed on chain A. For comparison PDB entry 1JPZ (chain A) with the S...
The bacterial Cytochrome P450 (CYP) BM3 (CYP102A1) is one of the most active CYP isoforms. BM3 mutan...
The bacterial Cytochrome P450 (CYP) BM3 (CYP102A1) is one of the most active CYP isoforms. BM3 mutan...
Two novel P450 heme iron ligand sets were generated by directed mutagenesis of the flavocytochrome P...
<p>(Top) Ribbon views of Mt-trHbN, Mt-trHbO, and Cj-trHbP, including the heme-Fe group (red) and the...
<p>(A) shows the H-bonding network between the propionate groups of heme <i>a</i> and the amino acid...
A nine heme group containing cytochrome c isolated from the soluble and membrane fractions of Desulf...
The crystal structure of bovine Complex III (PDB ID: 2A06) is shown on the left side with separate c...
<p>Residues lining the heme distal pocket are indicated (one letter code) and shown in green for the...
<p>(A) The whole complex structure. CYP2B6.1 is shown by ribbon, heme and AM are shown by ball-and-s...
Crystal data, data collection and structure refinement of CYP BM3 M11 mutant in complex with DTT.</p
<p>A) Cartoon representation of the LepHO-C26S-stop structure. B) Arrangement of the most relevant a...
Heme group, His25 and DTT from the 3D structure of DTT binding to rat heme oxygenase (PDB entry 3I9T...
Panels A and B show two discrete binding modes for compound 1a in the active site of CYP3A4 with eit...
<p>(A) Overview of Isd–NEAT domains; the heme molecule and primary/secondary tyrosine residues on th...