3-(4-Chlorophenyl)-5-(4-methoxyphenyl)-diarylisoxazoles is one of the compounds in a series of diarlyisoxazoles which in known to have anticarcinogenic properties. The three step synthesis of this product includes the synthesis of (E)-3-(4-Chlorophenyl)-1-(4-methoxyphenyl)-2-propen-1-one (through an Aldol Reaction) and 2,3-dibromo-3-(4-chlorophenyl)-1-(4-methoxyphenyl)-propan-1-one (through dihalogenation). The second product is then subjected to hydroxylamine*hydrochloride allowing for the formation of the final product, 3-(4-Chlorophenyl)-5-(4-methoxyphenyl)- diarylisoxazoles. The first step of the three step synthesis was preformed with the starting products, (non-substituted) benzaldehyde and acetophenone. This allowed for comparisons t...
Some 3,5-dimethyl-, 3-methyl 5-phenyl-, and 3,5-diphenyl-4-benzeneazo-isoxazoles have been synthesi...
A series of novel 6-fluoro-3-(4-piperidinyl)-1,2-benzisoxazole derivatives 5(a-m) were synthesized w...
Aim. Modern medicine widely applies drugs from the group of 1,2,4-triazole (fluconazole, triazolam, ...
The convenient regioselective scalable synthesis of 3,4-diaryl-5-carboxy-4,5-dihydroisoxazole 2-oxid...
The synthesis and cytotoxic activity studies of a new series of cyclic amine containing benzoxazole ...
The work behind my doctoral thesis has been focused on the study of reactivity of 3,5-dimethyl-4-nit...
The treatment of 4-{[(1E)-(2,4-dichlorophenyl)methylene]amino}-5-methyl-2,4-dihydro-3H-1,2,4-triazol...
1-Aryl-3-phenethylamino-1-propanone hydrochlorides 1-10, which are potentialpotent cytotoxic agents,...
A series of novel indole-containing diarylisoxazoles has been synthesised, based on our previous wor...
1669-16732-Chloro-1,4-phenylenedioxy-bis-acetyl hydrazine 1 on reacting with aromatic carboxylic a...
The rapid development of new "civilization diseases" is one of the negative manifestations of modern...
A series of 3-aryl-5-styrylisoxazoline/ 3,5-diarylisoxazoline derivatives were synthesized by the re...
We have developed a new safe and easy route for the synthesis of 1,3-dimethyl-1,2,3-triazolium deriv...
A series of novel indole-containing diarylisoxazoles has been synthesised, based on our previous wor...
4,5-Diarylisoxazoles are potent antiproliferative tubulin-targeting agents. Their isomeric 3,4-diary...
Some 3,5-dimethyl-, 3-methyl 5-phenyl-, and 3,5-diphenyl-4-benzeneazo-isoxazoles have been synthesi...
A series of novel 6-fluoro-3-(4-piperidinyl)-1,2-benzisoxazole derivatives 5(a-m) were synthesized w...
Aim. Modern medicine widely applies drugs from the group of 1,2,4-triazole (fluconazole, triazolam, ...
The convenient regioselective scalable synthesis of 3,4-diaryl-5-carboxy-4,5-dihydroisoxazole 2-oxid...
The synthesis and cytotoxic activity studies of a new series of cyclic amine containing benzoxazole ...
The work behind my doctoral thesis has been focused on the study of reactivity of 3,5-dimethyl-4-nit...
The treatment of 4-{[(1E)-(2,4-dichlorophenyl)methylene]amino}-5-methyl-2,4-dihydro-3H-1,2,4-triazol...
1-Aryl-3-phenethylamino-1-propanone hydrochlorides 1-10, which are potentialpotent cytotoxic agents,...
A series of novel indole-containing diarylisoxazoles has been synthesised, based on our previous wor...
1669-16732-Chloro-1,4-phenylenedioxy-bis-acetyl hydrazine 1 on reacting with aromatic carboxylic a...
The rapid development of new "civilization diseases" is one of the negative manifestations of modern...
A series of 3-aryl-5-styrylisoxazoline/ 3,5-diarylisoxazoline derivatives were synthesized by the re...
We have developed a new safe and easy route for the synthesis of 1,3-dimethyl-1,2,3-triazolium deriv...
A series of novel indole-containing diarylisoxazoles has been synthesised, based on our previous wor...
4,5-Diarylisoxazoles are potent antiproliferative tubulin-targeting agents. Their isomeric 3,4-diary...
Some 3,5-dimethyl-, 3-methyl 5-phenyl-, and 3,5-diphenyl-4-benzeneazo-isoxazoles have been synthesi...
A series of novel 6-fluoro-3-(4-piperidinyl)-1,2-benzisoxazole derivatives 5(a-m) were synthesized w...
Aim. Modern medicine widely applies drugs from the group of 1,2,4-triazole (fluconazole, triazolam, ...