International audienceGenes involved in major biological functions, such as reproductive or cognitive functions, are choice targets for natural selection. However, the extent to which these genes are affected by selective pressures remains undefined. The apparent clustering of these genes on sex chromosomes makes this genomic region an attractive model system to study the effects of evolutionary forces. In the present study, we analysed the genetic diversity of a X-linked microsatellite in 1410 X-chromosomes from 10 different human populations. Allelic frequency distributions revealed an unexpected discrepancy between the sexes. By evaluating the different scenarios that could have led to this pattern, we show that sex-specific selection on...
The X and Y chromosomes of humans and other mammals both have very atypical gene contents. The degen...
The evolution of female choice mechanisms favouring males of their own kind is considered a crucial ...
Intra-genomic conflict has the potential to cause widespread changes in patterns of genetic diversit...
Comparisons of levels of variability on the autosomes and X chromosome can be used to test hypothese...
International audienceSexually antagonistic (SA) selection, a form of selection that can occur when ...
The unique mode of inheritance and regulatory mechanisms of the X chromosome has resulted in distinc...
Abstract Background The transmission pattern of the h...
The X chromosome constitutes a unique genomic environment because it is present in one copy in males...
We describe here the results of a search of Mendelian inheritance in man, GENDIAG and other sources ...
Contrasting the genetic diversity of the human X chromosome (X) and autosomes has facilitated unders...
<div><p>The X chromosome constitutes a unique genomic environment because it is present in one copy ...
The ability of detecting adaptive (positive) selection in the genome has opened the possibility of u...
It has long been believed that the male-specific region of the human Y chromosome (MSY) is genetical...
Sexually Antagonistic (SA) selection can occur when, within a species, the two sexes have different ...
Due to its hemizygous inheritance and role in sex determination, the X-chromosome is expected to pla...
The X and Y chromosomes of humans and other mammals both have very atypical gene contents. The degen...
The evolution of female choice mechanisms favouring males of their own kind is considered a crucial ...
Intra-genomic conflict has the potential to cause widespread changes in patterns of genetic diversit...
Comparisons of levels of variability on the autosomes and X chromosome can be used to test hypothese...
International audienceSexually antagonistic (SA) selection, a form of selection that can occur when ...
The unique mode of inheritance and regulatory mechanisms of the X chromosome has resulted in distinc...
Abstract Background The transmission pattern of the h...
The X chromosome constitutes a unique genomic environment because it is present in one copy in males...
We describe here the results of a search of Mendelian inheritance in man, GENDIAG and other sources ...
Contrasting the genetic diversity of the human X chromosome (X) and autosomes has facilitated unders...
<div><p>The X chromosome constitutes a unique genomic environment because it is present in one copy ...
The ability of detecting adaptive (positive) selection in the genome has opened the possibility of u...
It has long been believed that the male-specific region of the human Y chromosome (MSY) is genetical...
Sexually Antagonistic (SA) selection can occur when, within a species, the two sexes have different ...
Due to its hemizygous inheritance and role in sex determination, the X-chromosome is expected to pla...
The X and Y chromosomes of humans and other mammals both have very atypical gene contents. The degen...
The evolution of female choice mechanisms favouring males of their own kind is considered a crucial ...
Intra-genomic conflict has the potential to cause widespread changes in patterns of genetic diversit...