Home urine C-peptide creatinine ratio (UCPCR) testing can identify type 2 and MODY in pediatric diabetes.
- Besser, R.
- Shields, Beverley
- Hammersley, S.
- Colclough, Kevin
- McDonald, Timothy J.
- Gray, Z.
- Heywood, J. J. N.
- Barrett, T. G.
- Hattersley, Andrew T.
DOIAbstract
Making the correct diabetes diagnosis in children is crucial for lifelong management. Type 2 diabetes and maturity onset diabetes of the young (MODY) are seen in the pediatric setting, and can be difficult to discriminate from type 1 diabetes. Postprandial urinary C-peptide creatinine ratio (UCPCR) is a non-invasive measure of endogenous insulin secretion that has not been tested as a diagnostic tool in children or in patients with diabetes duration <5 yr. We aimed to assess whether UCPCR can discriminate type 1 diabetes from MODY and type 2 in pediatric diabetes.This article is freely available via Open Access. Click on the 'Additional Link' above to access the full-text from the publisher's site.G0800661/Medical Research Council/United Ki...
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