Beta cell function and ongoing autoimmunity in long-standing, childhood onset type 1 diabetes.

Multinational study in children and adolescents with newly diagnosed type 1 diabetes: association of age, ketoacidosis, HLA status, and autoantibodies on residual beta-cell function and glycemic control 12 months after diagnosis

Mortensen, H B
Swift, P G F
Holl, R W
Hougaard, P
Hansen, L
Bjoerndalen, H
de Beaufort, C E
Knipp, M
Schoenle, E J

January 2010

OBJECTIVE: To identify predictors of residual beta-cell function and glycemic control during the fir...

Multinational study in children and adolescents with newly diagnosed type 1 diabetes: association of agem ketoacidosis,HLA status, and autoantibodies on residual beta-cell function and glycemic control 12 months after diagnosis.

H.B. MORTENSEN
P.G. SWIFT
R.W. HOLL
P. HOUGAARD
L. HANSEN
H. BJOERNDALEN
C.E. DE BEAUFORT
M. KNIP
VANELLI, Maurizio

January 2010

OBJECTIVE: To identify predictors of residual beta-cell function and glycemic control during the fir...

Congenital beta cell defects are not associated with markers of islet autoimmunity, even in the context of high genetic risk for type 1 diabetes

Wyatt, R. C.
Hagopian, W. A.
Roep, B. O.
Patel, K. A.
Resnick, B.
Dobbs, R.
Hudson, M.
De Franco, E.
Ellard, S.
Flanagan, S. E.
Hattersley, A. T.
Oram, R. A.
Johnson, M. B.

May 2022

AIMS/HYPOTHESIS: A key unanswered question in type 1 diabetes is whether beta cells initiate their o...

Beta cell function and ongoing autoimmunity in long-standing, childhood onset type 1 diabetes.

Williams, G. M.
Long, A. E.
Wilson, I. V.
Aitken, R. J.
Wyatt, R. C.
McDonald, Timothy J.
Wong, F. S.
Hattersley, Andrew T.
Williams, A. J. K.
Bingley, P. J.
Gillespie, K. M.

September 2016

This study aimed to determine the frequency of residual beta cell function in individuals with long-...

Beta cell function and ongoing autoimmunity in long-standing, childhood onset type 1 diabetes

Williams, Georgina M.
Long, Anna E.
Wilson, Isabel V.
Aitken, Rachel J.
Wyatt, Rebecca C.
McDonald, Timothy J.
Wong, Florence Susan
Hattersley, Andrew T.
Williams, Alistair J. K.
Bingley, Polly J.
Gillespie, Kathleen M.

December 2016

Aims/hypothesis This study aimed to determine the frequency of residual beta cell function in indiv...

Islet autoantibodies and residual beta cell function in type 1 diabetes children followed for 3-6 years

Sorensen, J. S.
Vaziri Sani, Fariba
Maziarz, M.
Kristensen, K.
Ellerman, A.
Breslow, N.
Lernmark, Åke
Pociot, F.
Brorsson, C.
Birkebaek, N. H.

January 2012

Aims: To test if islet autoantibodies at diagnosis of type 1 diabetes (T1DM) and after 3-6 years wit...

Residual beta-cell function in diabetes children followed and diagnosed in the TEDDY study compared to community controls.

Steck, A.K.
Larsson, H.E.
Liu, X.
Veijola, R.
Toppari, J.
Hagopian, W.A.
Haller, M.J.
Ahmed, S.
Akolkar, B.
Lernmark, A.
Rewers, M.J.
Krischer, J.P.
TEDDY Study Group (Ziegler, A.-G.

January 2017

ObjectiveTo explore whether children diagnosed with type 1 diabetes during islet autoantibody survei...

Residual beta-cell function in diabetes children followed and diagnosed in the TEDDY study compared to community controls

Steck, Andrea K
Larsson, Helena Elding
Liu, Xiang
Veijola, Riitta
Toppari, Jorma
Hagopian, William A.
Haller, Michael J.
Ahmed, Simi
Akolkar, Beena
Lernmark, Åke
Rewers, Marian J.
Krischer, Jeffrey P

January 2017

Objective: To explore whether children diagnosed with type 1 diabetes during islet autoantibody surv...

The majority of patients with long-duration type 1 diabetes are insulin microsecretors and have functioning beta cells

Oram, RA
Jones, AG
Besser, REJ
Knight, BA
Shields, BM
Brown, RJ
Hattersley, AT
McDonald, TJ

September 2018

PublishedThis is the final version of the article. Available from Springer Verlag via the DOI in thi...

Multinational study in children and adolescents with newly diagnosed type 1 diabetes: Association of age, ketoacidosis, HLA status, and autoantibodies on residual beta-cell function and glycemic control 12 months after diagnosis

Mortensen, H. B.
Swift, P. G.
Holl, R. W.
Hougaard, P.
Hansen, L.
Bjoerndalen, H.
De Beaufort, Carine
Knip, M.

January 2010

peer reviewedObjective: To identify predictors of residual beta-cell function and glycemic control d...

Loss of CXCR3 expression on memory B cells in individuals with long-standing type 1 diabetes

Powell, Wendy E.
Hanna, Stephanie J.
Hocter, Claire N.
Robinson, Emma
Davies, Joanne
Dunseath, Gareth J.
Luzio, Stephen
Farewell, Daniel
Wen, Li
Dayan, Colin M.
Price, David A.
Ladell, Kristin
Wong, F. Susan

August 2018

Aims/hypothesis Islet-specific autoantibodies can predict the development of type 1 diabetes. Howeve...

Residual β cell function in long-term type 1 diabetes associates with reduced incidence of hypoglycemia

Gubitosi-Klug, Rose A
Braffett, Barbara H
Hitt, Susan
Arends, Valerie
Uschner, Diane
Jones, Kimberly
Diminick, Lisa
Karger, Amy B
Paterson, Andrew D
Roshandel, Delnaz
Marcovina, Santica
Lachin, John M
Steffes, Michael
Palmer, Jerry P

February 2021

BACKGROUND: We investigated residual β cell function in Diabetes Control and Complications Trial/Epi...

Islet autoantibody phenotypes and incidence in children at increased risk for type 1 diabetes.

Giannopoulou, E.Z.
Winkler, C.
Chmiel, R.
Matzke, C.
Scholz, M.
Beyerlein, A.
Achenbach, P.
Bonifacio, E.
Ziegler, A.-G.

January 2015

AIMS/HYPOTHESIS: Autoantibodies that precede type 1 diabetes frequently develop in early childhood a...

Circulating C-peptide levels in living children and young people and pancreatic beta cell loss in pancreas donors across type 1 diabetes disease duration.

Carr, ALJ
Inshaw, JRJ
Flaxman, CS
Leete, P
Wyatt, RC
Russell, LA
Palmer, M
Prasolov, D
Worthington, T
Hull, B
Wicker, LS
Dunger, DB
Oram, RA
Morgan, NG
Todd, JA
Richardson, SJ
Besser, REJ

May 2022

This is the author accepted manuscript. The final version is available from the American Diabetes As...

Beta cell function in participants with single or multiple islet autoantibodies at baseline in the TEDDY Family Prevention Study:TEFA

Martinez, M. M. (Maria Månsson)
Salami, F. (Falastin)
Larsson, H. E. (Helena Elding)
Toppari, J. (Jorma)
Lernmark, Å. (Åke)
Kero, J. (Jukka)
Veijola, R. (Riitta)
Koskenniemi, J. J. (Jaakko J.)
Tossavainen, P. (Päivi)
Lundgren, M. (Markus)
Borg, H. (Henrik)
Katsarou, A. (Anastasia)
Maziarz, M. (Marlena)
Törn, C. (Carina)
, T. T. (The TEDDY Family (TEFA) Study Group)

January 2021

Abstract Aim: The aim of the present study was to assess beta cell function based on an oral glucos...

Multinational study in children and adolescents with newly diagnosed type 1 diabetes: association of age, ketoacidosis, HLA status, and autoantibodies on residual beta-cell function and glycemic control 12 months after diagnosis

Mortensen, H B
Swift, P G F
Holl, R W
Hougaard, P
Hansen, L
Bjoerndalen, H
de Beaufort, C E
Knipp, M
Schoenle, E J

January 2010

OBJECTIVE: To identify predictors of residual beta-cell function and glycemic control during the fir...

Multinational study in children and adolescents with newly diagnosed type 1 diabetes: association of agem ketoacidosis,HLA status, and autoantibodies on residual beta-cell function and glycemic control 12 months after diagnosis.

H.B. MORTENSEN
P.G. SWIFT
R.W. HOLL
P. HOUGAARD
L. HANSEN
H. BJOERNDALEN
C.E. DE BEAUFORT
M. KNIP
VANELLI, Maurizio

January 2010

OBJECTIVE: To identify predictors of residual beta-cell function and glycemic control during the fir...

Congenital beta cell defects are not associated with markers of islet autoimmunity, even in the context of high genetic risk for type 1 diabetes

Wyatt, R. C.
Hagopian, W. A.
Roep, B. O.
Patel, K. A.
Resnick, B.
Dobbs, R.
Hudson, M.
De Franco, E.
Ellard, S.
Flanagan, S. E.
Hattersley, A. T.
Oram, R. A.
Johnson, M. B.

May 2022

AIMS/HYPOTHESIS: A key unanswered question in type 1 diabetes is whether beta cells initiate their o...

Beta cell function and ongoing autoimmunity in long-standing, childhood onset type 1 diabetes.

Williams, G. M.
Long, A. E.
Wilson, I. V.
Aitken, R. J.
Wyatt, R. C.
McDonald, Timothy J.
Wong, F. S.
Hattersley, Andrew T.
Williams, A. J. K.
Bingley, P. J.
Gillespie, K. M.

September 2016

This study aimed to determine the frequency of residual beta cell function in individuals with long-...

Beta cell function and ongoing autoimmunity in long-standing, childhood onset type 1 diabetes

Williams, Georgina M.
Long, Anna E.
Wilson, Isabel V.
Aitken, Rachel J.
Wyatt, Rebecca C.
McDonald, Timothy J.
Wong, Florence Susan
Hattersley, Andrew T.
Williams, Alistair J. K.
Bingley, Polly J.
Gillespie, Kathleen M.

December 2016

Aims/hypothesis This study aimed to determine the frequency of residual beta cell function in indiv...

Islet autoantibodies and residual beta cell function in type 1 diabetes children followed for 3-6 years

Sorensen, J. S.
Vaziri Sani, Fariba
Maziarz, M.
Kristensen, K.
Ellerman, A.
Breslow, N.
Lernmark, Åke
Pociot, F.
Brorsson, C.
Birkebaek, N. H.

January 2012

Aims: To test if islet autoantibodies at diagnosis of type 1 diabetes (T1DM) and after 3-6 years wit...

Residual beta-cell function in diabetes children followed and diagnosed in the TEDDY study compared to community controls.

Steck, A.K.
Larsson, H.E.
Liu, X.
Veijola, R.
Toppari, J.
Hagopian, W.A.
Haller, M.J.
Ahmed, S.
Akolkar, B.
Lernmark, A.
Rewers, M.J.
Krischer, J.P.
TEDDY Study Group (Ziegler, A.-G.

January 2017

ObjectiveTo explore whether children diagnosed with type 1 diabetes during islet autoantibody survei...

Residual beta-cell function in diabetes children followed and diagnosed in the TEDDY study compared to community controls

Steck, Andrea K
Larsson, Helena Elding
Liu, Xiang
Veijola, Riitta
Toppari, Jorma
Hagopian, William A.
Haller, Michael J.
Ahmed, Simi
Akolkar, Beena
Lernmark, Åke
Rewers, Marian J.
Krischer, Jeffrey P

January 2017

Objective: To explore whether children diagnosed with type 1 diabetes during islet autoantibody surv...

The majority of patients with long-duration type 1 diabetes are insulin microsecretors and have functioning beta cells

Oram, RA
Jones, AG
Besser, REJ
Knight, BA
Shields, BM
Brown, RJ
Hattersley, AT
McDonald, TJ

September 2018

PublishedThis is the final version of the article. Available from Springer Verlag via the DOI in thi...

Multinational study in children and adolescents with newly diagnosed type 1 diabetes: Association of age, ketoacidosis, HLA status, and autoantibodies on residual beta-cell function and glycemic control 12 months after diagnosis

Mortensen, H. B.
Swift, P. G.
Holl, R. W.
Hougaard, P.
Hansen, L.
Bjoerndalen, H.
De Beaufort, Carine
Knip, M.

January 2010

peer reviewedObjective: To identify predictors of residual beta-cell function and glycemic control d...

Loss of CXCR3 expression on memory B cells in individuals with long-standing type 1 diabetes

Powell, Wendy E.
Hanna, Stephanie J.
Hocter, Claire N.
Robinson, Emma
Davies, Joanne
Dunseath, Gareth J.
Luzio, Stephen
Farewell, Daniel
Wen, Li
Dayan, Colin M.
Price, David A.
Ladell, Kristin
Wong, F. Susan

August 2018

Aims/hypothesis Islet-specific autoantibodies can predict the development of type 1 diabetes. Howeve...

Residual β cell function in long-term type 1 diabetes associates with reduced incidence of hypoglycemia

Gubitosi-Klug, Rose A
Braffett, Barbara H
Hitt, Susan
Arends, Valerie
Uschner, Diane
Jones, Kimberly
Diminick, Lisa
Karger, Amy B
Paterson, Andrew D
Roshandel, Delnaz
Marcovina, Santica
Lachin, John M
Steffes, Michael
Palmer, Jerry P

February 2021

BACKGROUND: We investigated residual β cell function in Diabetes Control and Complications Trial/Epi...

Islet autoantibody phenotypes and incidence in children at increased risk for type 1 diabetes.

Giannopoulou, E.Z.
Winkler, C.
Chmiel, R.
Matzke, C.
Scholz, M.
Beyerlein, A.
Achenbach, P.
Bonifacio, E.
Ziegler, A.-G.

January 2015

AIMS/HYPOTHESIS: Autoantibodies that precede type 1 diabetes frequently develop in early childhood a...

Circulating C-peptide levels in living children and young people and pancreatic beta cell loss in pancreas donors across type 1 diabetes disease duration.

Carr, ALJ
Inshaw, JRJ
Flaxman, CS
Leete, P
Wyatt, RC
Russell, LA
Palmer, M
Prasolov, D
Worthington, T
Hull, B
Wicker, LS
Dunger, DB
Oram, RA
Morgan, NG
Todd, JA
Richardson, SJ
Besser, REJ

May 2022

This is the author accepted manuscript. The final version is available from the American Diabetes As...

Beta cell function in participants with single or multiple islet autoantibodies at baseline in the TEDDY Family Prevention Study:TEFA

Martinez, M. M. (Maria Månsson)
Salami, F. (Falastin)
Larsson, H. E. (Helena Elding)
Toppari, J. (Jorma)
Lernmark, Å. (Åke)
Kero, J. (Jukka)
Veijola, R. (Riitta)
Koskenniemi, J. J. (Jaakko J.)
Tossavainen, P. (Päivi)
Lundgren, M. (Markus)
Borg, H. (Henrik)
Katsarou, A. (Anastasia)
Maziarz, M. (Marlena)
Törn, C. (Carina)
, T. T. (The TEDDY Family (TEFA) Study Group)

January 2021

Abstract Aim: The aim of the present study was to assess beta cell function based on an oral glucos...

Multinational study in children and adolescents with newly diagnosed type 1 diabetes: association of age, ketoacidosis, HLA status, and autoantibodies on residual beta-cell function and glycemic control 12 months after diagnosis

Mortensen, H B
Swift, P G F
Holl, R W
Hougaard, P
Hansen, L
Bjoerndalen, H
de Beaufort, C E
Knipp, M
Schoenle, E J

January 2010

OBJECTIVE: To identify predictors of residual beta-cell function and glycemic control during the fir...

Multinational study in children and adolescents with newly diagnosed type 1 diabetes: association of agem ketoacidosis,HLA status, and autoantibodies on residual beta-cell function and glycemic control 12 months after diagnosis.

H.B. MORTENSEN
P.G. SWIFT
R.W. HOLL
P. HOUGAARD
L. HANSEN
H. BJOERNDALEN
C.E. DE BEAUFORT
M. KNIP
VANELLI, Maurizio

January 2010

OBJECTIVE: To identify predictors of residual beta-cell function and glycemic control during the fir...

Congenital beta cell defects are not associated with markers of islet autoimmunity, even in the context of high genetic risk for type 1 diabetes

Wyatt, R. C.
Hagopian, W. A.
Roep, B. O.
Patel, K. A.
Resnick, B.
Dobbs, R.
Hudson, M.
De Franco, E.
Ellard, S.
Flanagan, S. E.
Hattersley, A. T.
Oram, R. A.
Johnson, M. B.

May 2022

AIMS/HYPOTHESIS: A key unanswered question in type 1 diabetes is whether beta cells initiate their o...

Beta cell function and ongoing autoimmunity in long-standing, childhood onset type 1 diabetes.

Abstract

Extracted data

Beta cell function and ongoing autoimmunity in long-standing, childhood onset type 1 diabetes.

Abstract

Extracted data

Related items

Related items