Bacteriophage-liposomal therapy in complex treatment of purulent wounds in patients with antibiotic allergy

В настоящее время возникла проблема альтернативной антибиотикотерапии для пациентов с аллергией на антибиотики. Одним из альтернативных методов лечения гнойной хирургической инфекции у данных пациентов является использование бактериофагов и липосом. В работе представлены результаты комплексного лечения больных с гнойными ранами мягких тканней и аллергией на антибиотики с использованием бактериофаголипосомальной терапии, которая может быть рекомендована в качестве метода выбора для лечения воспалительных и гнойных поражений мягких тканей у этих пациентов. Introduction. Nowadays there is a problem of alternative to antibiotic therapy for patients who have allergy to antibiotics. One of the alternative treatment of purulent surgical infection in patients with allergic reactions to antibiotics is the use of bacteriophages and liposomes. Aim. To improve the results of treatment of purulent wounds of soft tissues in patients with allergies to antibiotics using bacteriophages in treatment and liposomes. Material and methods. Clinical studies conducted in 140 patients with purulent-inflammatory diseases of soft tissues that were treated in Poltava District Central Hospital, City Clinical Hospital № 3 and Poltava Garrison Military Hospital. Conclusion. Using in the treatment of inflammatory lesions of purulent soft tissue bacteriophageliposomal therapy developed by our method leads to a statistically significant decrease in duration of pain and swelling tissue, accelerate wound cleansing and the emergence of active granulation and accelerates wound healing. Use bacteriophage-liposomal therapy in the treatment of septic wounds improves the above figures also in patients who have an allergic reaction to antibiotics and can be recommended as a method of choice for the treatment of inflammatory and purulent soft tissue lesions in these patient