International audienceIon-induced cell killing has been reported to depend on irradiation dose but also projectile parameters. In this paper we focus on two approaches developed and extensively used to predict cell survival in response to ion irradiation: the Local Effect Model and the Katz Model. These models are based on a track-structure description summarized in the concept of radial dose. This latter is sensitive to ion parameters and gives to both models the ability to predict some important radiobiological features for ion irradiations. Radial dose is however an average quantity, which does not include stochastic effects. These radiation-intrinsic effects are investigated by means of a Monte-Carlo simulation of dose deposition. We sh...
Katz’s theory of cellular track structure (1) is an amorphous analytical model which applies a set o...
A simple model for cell survival which is valid also at high dose has been developed. The model para...
Studies of the structure of particle tracks have led to models of track effects based on radial dose...
International audienceIon-induced cell killing has been reported to depend on irradiation dose but a...
32 pages ; 8 figuresIon-induced cell killing has been reported to depend on the irradiation dose but...
simulation Abstract: Ion-induced cell killing has been reported to depend on the irradiation dose bu...
International audienceThe Local Effect Model (LEM) is a track-structure model that was developed to ...
Both the microdosimetric kinetic model (MKM) and the local effect model(LEM) can be used to calculat...
The use of computational methods to improve the understanding of biological responses to various typ...
The average or amorphous track model uses the response of a system to gamma-rays and the radial dist...
To present details of the recent version of the 'Local Effect Model' (LEM), that has been developed ...
Ionizing radiation is a health hazard to humans, but is exploited at the same time in various applic...
Katz’s theory of cellular track structure (1) is an amorphous analytical model which applies a set o...
A simple model for cell survival which is valid also at high dose has been developed. The model para...
Studies of the structure of particle tracks have led to models of track effects based on radial dose...
International audienceIon-induced cell killing has been reported to depend on irradiation dose but a...
32 pages ; 8 figuresIon-induced cell killing has been reported to depend on the irradiation dose but...
simulation Abstract: Ion-induced cell killing has been reported to depend on the irradiation dose bu...
International audienceThe Local Effect Model (LEM) is a track-structure model that was developed to ...
Both the microdosimetric kinetic model (MKM) and the local effect model(LEM) can be used to calculat...
The use of computational methods to improve the understanding of biological responses to various typ...
The average or amorphous track model uses the response of a system to gamma-rays and the radial dist...
To present details of the recent version of the 'Local Effect Model' (LEM), that has been developed ...
Ionizing radiation is a health hazard to humans, but is exploited at the same time in various applic...
Katz’s theory of cellular track structure (1) is an amorphous analytical model which applies a set o...
A simple model for cell survival which is valid also at high dose has been developed. The model para...
Studies of the structure of particle tracks have led to models of track effects based on radial dose...