The efficacy and safety of maternal tenofovir disoproxil fumarate (TDF) in reducing mother-to-infant hepatitis B virus (HBV) transmissions is not clearly understood. We conducted a prospective, multicenter trial and enrolled 118 hepatitis B surface antigen (HBsAg)- and hepatitis B e antigen-positive pregnant women with HBV DNA 7.5 log(10) IU/mL. The mothers received no medication (control group, n=56, HBV DNA 8.22 +/- 0.39 log(10) IU/mL) or TDF 300 mg daily (TDF group, n=62, HBV DNA 8.18 +/- 0.47 log(10) IU/mL) from 30-32 weeks of gestation until 1 month postpartum. Primary outcome was infant HBsAg at 6 months old. At delivery, the TDF group had lower maternal HBV DNA levels (4.29 +/- 0.93 versus 8.10 +/- 0.56 log(10) IU/mL, P<0.0001). O...
BACKGROUND/PURPOSE: Use of tenofovir disoproxil fumarate (TDF) improves patient outcomes in preventi...
BACKGROUNDPregnant women with an elevated viral load of hepatitis B virus (HBV) have a risk of trans...
Background/Aims There have been numerous efforts to reduce mother-to-child transmission (MTCT) of he...
International audienceMother-to-child transmission is the major cause of chronic hepatitis B virus (...
International audienceMother-to-child transmission is the major cause of chronic hepatitis B virus (...
International audienceMother-to-child transmission is the major cause of chronic hepatitis B virus (...
International audienceMother-to-child transmission is the major cause of chronic hepatitis B virus (...
Background/Aims To prevent the perinatal transmission of hepatitis B virus (HBV) from mother to chil...
Background: Few data are available regarding the use of tenofovir disoproxil fumarate (TDF) during p...
BACKGROUND: Pregnant women with an elevated viral load of hepatitis B virus (HBV) have a risk of tra...
INTRODUCTION:Hepatitis B virus (HBV) remains a public health threat and the main route of transmissi...
INTRODUCTION: Hepatitis B virus (HBV) remains a public health threat and the main route of transmiss...
Background: Chronic hepatitis B virus (HBV) infection is complicated by cirrhosis and liver cancer. ...
Background: Chronic hepatitis B virus (HBV) infection is complicated by cirrhosis and liver cancer. ...
Background: Chronic hepatitis B virus (HBV) infection is complicated by cirrhosis and liver cancer. ...
BACKGROUND/PURPOSE: Use of tenofovir disoproxil fumarate (TDF) improves patient outcomes in preventi...
BACKGROUNDPregnant women with an elevated viral load of hepatitis B virus (HBV) have a risk of trans...
Background/Aims There have been numerous efforts to reduce mother-to-child transmission (MTCT) of he...
International audienceMother-to-child transmission is the major cause of chronic hepatitis B virus (...
International audienceMother-to-child transmission is the major cause of chronic hepatitis B virus (...
International audienceMother-to-child transmission is the major cause of chronic hepatitis B virus (...
International audienceMother-to-child transmission is the major cause of chronic hepatitis B virus (...
Background/Aims To prevent the perinatal transmission of hepatitis B virus (HBV) from mother to chil...
Background: Few data are available regarding the use of tenofovir disoproxil fumarate (TDF) during p...
BACKGROUND: Pregnant women with an elevated viral load of hepatitis B virus (HBV) have a risk of tra...
INTRODUCTION:Hepatitis B virus (HBV) remains a public health threat and the main route of transmissi...
INTRODUCTION: Hepatitis B virus (HBV) remains a public health threat and the main route of transmiss...
Background: Chronic hepatitis B virus (HBV) infection is complicated by cirrhosis and liver cancer. ...
Background: Chronic hepatitis B virus (HBV) infection is complicated by cirrhosis and liver cancer. ...
Background: Chronic hepatitis B virus (HBV) infection is complicated by cirrhosis and liver cancer. ...
BACKGROUND/PURPOSE: Use of tenofovir disoproxil fumarate (TDF) improves patient outcomes in preventi...
BACKGROUNDPregnant women with an elevated viral load of hepatitis B virus (HBV) have a risk of trans...
Background/Aims There have been numerous efforts to reduce mother-to-child transmission (MTCT) of he...