Objectives: Endophenotypes in schizophrenia research is a contemporary approach to studying this heterogeneous mental illness, and several candidate neurophysiological markers (e.g. P50 sensory gating) and neuropsychological tests (e.g. Continuous Performance Test (CPT) and Wisconsin Card Sorting Test (WCST)) have been proposed. However, the clinical utility of a single marker appears to be limited. In the present study, we aimed to construct a diagnostic model incorporating P50 sensory gating with other neuropsychological tests in order to improve the clinical utility. Methods: We recruited clinically stable outpatients meeting DSM-IV criteria of schizophrenia and age-and gender-matched healthy controls. Participants underwent P50 sensory...
Background: Schizophrenia is a heterogeneous disorder with diverse presentations. The current and th...
Endophenotypes are quantitative, laboratory-based measures representing intermediate links in the pa...
Schizophrenia is a serious mental illness that manifests itself with inconsistent, complex, and chal...
OBJECTIVES: Endophenotypes in schizophrenia research is a contemporary approach to studying this het...
Objectives: Endophenotypes in schizophrenia research is a contemporary approach to studying this het...
International audienceP50 amplitude changes in dual click conditioning–testing procedure might be a ...
Objective: Cognitive deficits are core symptoms of schizophrenia; however, their pathophysiological ...
Objective: Numerous studies have reported P50 gating deficits in schizophrenia, though with mixed re...
International audienceBackgroundP50 amplitude changes in dual click conditioning–testing procedure m...
Background: Endophenotypes are quantitative, laboratory-based measures representing intermediate lin...
BackgroundAbnormal P50 response has been hypothesized to reflect the sensory gating deficit in schiz...
Many studies have found that the P50 sensory gating ratio in a paired click task is smaller in norma...
AbstractThe P50 is an early component of auditory evoked potentials and a measure of sensory gating ...
The present dissertation evaluated the P50 component of the event-related brain potential (ERP), an ...
Background: Individuals with an "Attenuated Psychosis Syndrome" (APS) have a 20-40% chance of develo...
Background: Schizophrenia is a heterogeneous disorder with diverse presentations. The current and th...
Endophenotypes are quantitative, laboratory-based measures representing intermediate links in the pa...
Schizophrenia is a serious mental illness that manifests itself with inconsistent, complex, and chal...
OBJECTIVES: Endophenotypes in schizophrenia research is a contemporary approach to studying this het...
Objectives: Endophenotypes in schizophrenia research is a contemporary approach to studying this het...
International audienceP50 amplitude changes in dual click conditioning–testing procedure might be a ...
Objective: Cognitive deficits are core symptoms of schizophrenia; however, their pathophysiological ...
Objective: Numerous studies have reported P50 gating deficits in schizophrenia, though with mixed re...
International audienceBackgroundP50 amplitude changes in dual click conditioning–testing procedure m...
Background: Endophenotypes are quantitative, laboratory-based measures representing intermediate lin...
BackgroundAbnormal P50 response has been hypothesized to reflect the sensory gating deficit in schiz...
Many studies have found that the P50 sensory gating ratio in a paired click task is smaller in norma...
AbstractThe P50 is an early component of auditory evoked potentials and a measure of sensory gating ...
The present dissertation evaluated the P50 component of the event-related brain potential (ERP), an ...
Background: Individuals with an "Attenuated Psychosis Syndrome" (APS) have a 20-40% chance of develo...
Background: Schizophrenia is a heterogeneous disorder with diverse presentations. The current and th...
Endophenotypes are quantitative, laboratory-based measures representing intermediate links in the pa...
Schizophrenia is a serious mental illness that manifests itself with inconsistent, complex, and chal...