Introduction: The hereditability of insulin resistance has been demonstrated in both familial and twin studies. The effects of renin-angiotensin-aldosterone system gene polymorphisms on insulin resistance remain inconclusive. Methods: This is a sibling-based association study. Polymorphisms of renin-angiotensin-aldosterone system genes were examined in 1113 hypertension and 676 normotension siblings from Chinese and Japanese hypertensive families. The generalized estimation equations method was used to compare the differences in metabolic variables between hypertension and normotensive siblings. Results: For the G-6A polymorphism of AGT, GG siblings had lower 2-h insulin than siblings carrying the A allele (p=0.006). Siblings with differe...
AIMS: Although the function of resistin in human biology is unclear, some evidence suggests resistin...
For details of the DESIR Study Group and the RISC study and investigators, see the ESM.International...
OBJECTIVE: To study the association between polymorphisms in the angiotensin converting enzyme (ACE)...
[[abstract]]Introduction: The hereditability of insulin resistance has been demonstrated in both fam...
[[abstract]]The clustering between hypertension and other metabolic abnormalities related to insulin...
The clustering between hypertension and other metabolic abnormalities related to insulin resistance ...
ABSTRACT: BACKGROUND: Genotype-phenotype association studies are typically based upon polymorphisms ...
[[abstract]]Aims: Although the function of resistin in human biology is unclear, some evidence sugge...
Copyright Lippincott-Raven Publishers. [Full text of this article is not available in the UHRA]Objec...
PURPOSE: To investigate how genetic polymorphisms of the renin-angiotensin-aldosterone system (RAAS)...
Aims: Studies suggest that adiponectin (APM1) and its receptors 1 and 2 (AdipoR1 and AdipoR2) play ...
Objective: Childhood primary hypertension has been increasing in parallel with the increase in obesi...
The peroxisome proliferator activated receptor (PPAR) gamma( 2) is a transcription factor that has b...
[[abstract]]The peroxisome proliferator activated receptor (PPAR) gamma (2) is a transcription facto...
Context: The aldosterone to renin ratio (ARR) is a marker of aldosterone excess, widely used to scre...
AIMS: Although the function of resistin in human biology is unclear, some evidence suggests resistin...
For details of the DESIR Study Group and the RISC study and investigators, see the ESM.International...
OBJECTIVE: To study the association between polymorphisms in the angiotensin converting enzyme (ACE)...
[[abstract]]Introduction: The hereditability of insulin resistance has been demonstrated in both fam...
[[abstract]]The clustering between hypertension and other metabolic abnormalities related to insulin...
The clustering between hypertension and other metabolic abnormalities related to insulin resistance ...
ABSTRACT: BACKGROUND: Genotype-phenotype association studies are typically based upon polymorphisms ...
[[abstract]]Aims: Although the function of resistin in human biology is unclear, some evidence sugge...
Copyright Lippincott-Raven Publishers. [Full text of this article is not available in the UHRA]Objec...
PURPOSE: To investigate how genetic polymorphisms of the renin-angiotensin-aldosterone system (RAAS)...
Aims: Studies suggest that adiponectin (APM1) and its receptors 1 and 2 (AdipoR1 and AdipoR2) play ...
Objective: Childhood primary hypertension has been increasing in parallel with the increase in obesi...
The peroxisome proliferator activated receptor (PPAR) gamma( 2) is a transcription factor that has b...
[[abstract]]The peroxisome proliferator activated receptor (PPAR) gamma (2) is a transcription facto...
Context: The aldosterone to renin ratio (ARR) is a marker of aldosterone excess, widely used to scre...
AIMS: Although the function of resistin in human biology is unclear, some evidence suggests resistin...
For details of the DESIR Study Group and the RISC study and investigators, see the ESM.International...
OBJECTIVE: To study the association between polymorphisms in the angiotensin converting enzyme (ACE)...