Acute myeloid leukemia (AML) with t(7;11)(p15;p15), which results in a NUP98-HOXA9 fusion, is a distinct entity, but this subtype has not been characterized in detail. In a comprehensive study comparing 11 such patients with another 482 adult patients, we found that those with t(7;11) were younger (P = 0.0076) and female (P = 0.0111), with almost all having the M2-subtype of AML (P < 0.0001). Even when those with low-risk karyotypes were excluded, patients with t(7;11) had poorer overall survival than the other AML group (median 13.5 and 20 months, respectively , P = 0.045) and poorer relapse-free survival (median 6 and 12 months, respectively, P = 0.003). The NUP98-HOXA9 fusion was strongly associated with KRAS and WT1 mutations (P = 0.015...
The t(8;21)(q22;q22) is the most common translocation in acute myeloid leukemia (AML). We describe t...
Acute myeloid leukemia (AML) with the t(8;21) (q22;q22) creating the AML1-ETO fusion gene is a disti...
Review on Renal cell carcinoma with t(X;1)(p11;p34) SFPQ/TFE3, with data on clinics, and the genes i...
The t(7;11)(p15;p15.4) has been reported to fuse the NUP98 gene (11p15), a component of the nuclear ...
Translocation (7;11)(p15;p15) is uncommon in acute myeloid leukemia (AML) and may have a predilectio...
A t(11;20)(p15;q11) is a rare but recurrent chromosomal aberration, reported in one case of polycyth...
Translocation (7;11)(p15;p15) is a recently characterized chromosomal abnormality that results in fu...
The t(7;11)(p15;p15) translocation is a recurrent genetic abnormality associated with acute myelogen...
In the last years, collaborative studies have joined to link the degree of genetic heterogeneity of ...
BACKGROUND: Translocation (8;21), t(8;21), is one of the most common cytogenetic abnormalities in ad...
The NUP98 gene at chromosome band 11p15 is known to be fused to a number of different partners in va...
This study was aimed to investigate the characteristics of 11 patients with acute myeloid leukemia (...
Background/aim: The chromosome translocation t(8;19)(p11;q13) has been reported in only six acute my...
Acute leukemias (ALs) of ambiguous lineage are a heterogeneous group of high-risk leukemias characte...
Acute myeloid leukaemia (AML) patients with either a t(15;17), t(8;21) or inv(16) at diagnosis have ...
The t(8;21)(q22;q22) is the most common translocation in acute myeloid leukemia (AML). We describe t...
Acute myeloid leukemia (AML) with the t(8;21) (q22;q22) creating the AML1-ETO fusion gene is a disti...
Review on Renal cell carcinoma with t(X;1)(p11;p34) SFPQ/TFE3, with data on clinics, and the genes i...
The t(7;11)(p15;p15.4) has been reported to fuse the NUP98 gene (11p15), a component of the nuclear ...
Translocation (7;11)(p15;p15) is uncommon in acute myeloid leukemia (AML) and may have a predilectio...
A t(11;20)(p15;q11) is a rare but recurrent chromosomal aberration, reported in one case of polycyth...
Translocation (7;11)(p15;p15) is a recently characterized chromosomal abnormality that results in fu...
The t(7;11)(p15;p15) translocation is a recurrent genetic abnormality associated with acute myelogen...
In the last years, collaborative studies have joined to link the degree of genetic heterogeneity of ...
BACKGROUND: Translocation (8;21), t(8;21), is one of the most common cytogenetic abnormalities in ad...
The NUP98 gene at chromosome band 11p15 is known to be fused to a number of different partners in va...
This study was aimed to investigate the characteristics of 11 patients with acute myeloid leukemia (...
Background/aim: The chromosome translocation t(8;19)(p11;q13) has been reported in only six acute my...
Acute leukemias (ALs) of ambiguous lineage are a heterogeneous group of high-risk leukemias characte...
Acute myeloid leukaemia (AML) patients with either a t(15;17), t(8;21) or inv(16) at diagnosis have ...
The t(8;21)(q22;q22) is the most common translocation in acute myeloid leukemia (AML). We describe t...
Acute myeloid leukemia (AML) with the t(8;21) (q22;q22) creating the AML1-ETO fusion gene is a disti...
Review on Renal cell carcinoma with t(X;1)(p11;p34) SFPQ/TFE3, with data on clinics, and the genes i...