Purpose: To determine whether an increase in tumor angiogenesis facilitates intravasation of colorectal epithelial cells, we compared intratumoral microvessel counts with the presence of circulating colorectal epithelial cells in the portal venous blood from patients with colorectal carcinomas, Experimental Design: Circulating colorectal epithelial cells were detected by a reverse transcription-PCR assay to amplify guanylyl cyclase C (GCC) transcripts. The extent of tumor vascularization was quantitatively assessed by immunohistochemical staining with anti-CD31 antibody. Results: Colorectal epithelial cells las measured by GCC mRNA expression) were detected in the portal venous blood in 30 of 58 patients (52%). The mean (+/ - SD) microvesse...
Angiogenesis plays an important role in the growth and progression of cancer. The regulation of tumo...
Copyright © 2014 Ievgenia Pastushenko et al. This is an open access article distributed under the Cr...
BACKGROUND: Recent studies have shown that the cyclooxygenase (COX) and the inducible nitric oxid...
Alterations in adhesion molecules, angiogenesis, and matrix metalloproteinases have been associated ...
PURPOSE: Angiogenesis, as measured by degree of microvessel density, has been associated with tumor ...
Summary The vasculanrsation of human primary colorectal carcinomas was studied immunohistochemically...
Angiogenesis is essential for the development ofhuman solid carcinomas. Many studies in vari-ous hum...
Angiogenesis is an essential requirement for the development, progression and metastasis of malignan...
Colon cancer is the fourth most common cause of cancer death in the world. It kills approximately 52...
Summary: Intravasation, active entry of cancer cells into the circulation, is often considered to be...
Contains fulltext : 59109.pdf (publisher's version ) (Closed access)In animal mode...
<div><p>Blood vessels in cancer</p><p>Intra-tumoral blood vessels are of supreme importance for tumo...
[[abstract]]Background: The main objective of this study was to determine whether there was a correl...
BACKGROUND AND OBJECTIVES: Angiogenesis is a complex multistep process that involves extracellular m...
Context.-5-Lipoxygenase (5-LO) is an arachidonic acid metabolizing enzyme, which has been demonstrat...
Angiogenesis plays an important role in the growth and progression of cancer. The regulation of tumo...
Copyright © 2014 Ievgenia Pastushenko et al. This is an open access article distributed under the Cr...
BACKGROUND: Recent studies have shown that the cyclooxygenase (COX) and the inducible nitric oxid...
Alterations in adhesion molecules, angiogenesis, and matrix metalloproteinases have been associated ...
PURPOSE: Angiogenesis, as measured by degree of microvessel density, has been associated with tumor ...
Summary The vasculanrsation of human primary colorectal carcinomas was studied immunohistochemically...
Angiogenesis is essential for the development ofhuman solid carcinomas. Many studies in vari-ous hum...
Angiogenesis is an essential requirement for the development, progression and metastasis of malignan...
Colon cancer is the fourth most common cause of cancer death in the world. It kills approximately 52...
Summary: Intravasation, active entry of cancer cells into the circulation, is often considered to be...
Contains fulltext : 59109.pdf (publisher's version ) (Closed access)In animal mode...
<div><p>Blood vessels in cancer</p><p>Intra-tumoral blood vessels are of supreme importance for tumo...
[[abstract]]Background: The main objective of this study was to determine whether there was a correl...
BACKGROUND AND OBJECTIVES: Angiogenesis is a complex multistep process that involves extracellular m...
Context.-5-Lipoxygenase (5-LO) is an arachidonic acid metabolizing enzyme, which has been demonstrat...
Angiogenesis plays an important role in the growth and progression of cancer. The regulation of tumo...
Copyright © 2014 Ievgenia Pastushenko et al. This is an open access article distributed under the Cr...
BACKGROUND: Recent studies have shown that the cyclooxygenase (COX) and the inducible nitric oxid...