Inhibition of Epstein-Barr Virus Lytic Cycle by RNA Interference

EB病毒與其他人類皰疹病毒科成員一樣具有兩種不同型態的生活史，包括潛伏期與溶裂期。然而於體外模式中，某些化學藥劑或細胞激素(例如：TPA：12-O-tetradecanoylphorbol-13-acetate、SB：n-sodium butyrate或是TGF-EBV(Epstein-Barr virus), like other human herpesviruses, possesses two phases in its life cycle: latent and lytic stages. In vitro, however, EBV can be triggered into lytic cycle in the presence of the chemicals or cytokines, such as 12-O-tetradecanoyl -phorbol-13-acetate(TPA), n-sodium butyrate(SB), or TGF-中文摘要---- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -Ⅰ 英文摘要---- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -Ⅱ 目錄---- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---Ⅳ 序論---- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---1 動機目的---- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -9 實驗材料---- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -10 實驗方法---- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -14 結果---- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---19 討論---- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---22 圖表---- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- ---26 參考文獻---- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- --- -4