SIMULATIONS OF SCANNED FOCUSSED ULTRASOUND HYPERTHERMIA: THE EFFECTS OF SCANNING SPEED, SCANNING PATTERN AND MULTIPLE TILTED TRANSDUCERS

A transient three-dimensional simulation program was developed to study the effects of scanning speed, scanning pattern, blood perfusion, transducer choice and multiple tilted transducers with overlapping foci during scanned focussed ultrasound hyperthermia. The results showed that (1) the temperature fluctuations increase linearly with decreasing scanning speed, (2) the temperature fluctuations are a weak, increasingly exponential function of the blood perfusion rate, and (3) that the largest temperature fluctuation is always located at the acoustical focal depth on the scan path independently of focal plane depth. Simulations using multiple scan paths showed that relatively uniform average temperature distributions can be achieved at the focal zone as long as the spacing between the concentric scans was not greater than the diameter of the focus of the power field. Finally, the results showed that using multiple tilted transducers with overlapping foci, increased focussing can be obtained at the focal depth