Polymer-peptide conjugates are a promising class of compounds, where polymers can be used to overcome some of the limitations associated with peptides intended for therapeutic and/or diagnostic applications. Linear polymers such as poly(ethylene glycol) can be conjugated through terminal moieties and have therefore limited loading capacities. In this research, functionalised linear poly(ethylene glycol)s are utilised for peptide conjugation, to increase their potential loading capacities. These poly(ethylene glycol) derivatives are conjugated to peptide sequences containing representative side-chain functionalised amino acids, using different conjugation chemistries, including copper-catalysed azide-alkyne cycloaddition, amide coupling and ...
Bioconjugates play an important role in several fields of biomolecular and bio-medicinal sciences. P...
A tri(ethylene glycol)-containing lactide analogue was synthesized via thiol–ene chemistry between ...
Poly(ethylene glycol)s grated onto suitably functionalized, crosslinked polystyrenes were introduced...
Polymer-peptide conjugates are a promising class of compounds, where polymers can be used to overcom...
Polymer-peptide conjugates are a promising class of compounds, where polymers can be used to overcom...
Polymer-peptide conjugates are a promising class of compounds, where polymers can be used to overcom...
We synthesized a library of 50 poly(ethylene glycol) (PEG) derivatives to expand the extent of conju...
Electroactive polymer-peptide conjugates have been synthesized by combining poly(3,4-ethylenedioxyth...
Over the last ten years the attention of the pharmaceutical industry has shifted away from small mol...
Clinically used peptides and antibodies can be modified to improve their therapeutic potential. As p...
Conjugation of proteins to well-defined polymers is a promising strategy for developing effective ta...
Polymer–peptide conjugates (also known as biohybrids) are attracting considerable attention as injec...
Linear polyether polyol (PEP) consisting of glycidol as repeating units is a flexible hydrophilic al...
Polyethylene glycol (PEG) at the moment is considered the leading polymer for protein conjugation in...
The field of drug delivery is fast expanding and its potentials have already been proved by the many...
Bioconjugates play an important role in several fields of biomolecular and bio-medicinal sciences. P...
A tri(ethylene glycol)-containing lactide analogue was synthesized via thiol–ene chemistry between ...
Poly(ethylene glycol)s grated onto suitably functionalized, crosslinked polystyrenes were introduced...
Polymer-peptide conjugates are a promising class of compounds, where polymers can be used to overcom...
Polymer-peptide conjugates are a promising class of compounds, where polymers can be used to overcom...
Polymer-peptide conjugates are a promising class of compounds, where polymers can be used to overcom...
We synthesized a library of 50 poly(ethylene glycol) (PEG) derivatives to expand the extent of conju...
Electroactive polymer-peptide conjugates have been synthesized by combining poly(3,4-ethylenedioxyth...
Over the last ten years the attention of the pharmaceutical industry has shifted away from small mol...
Clinically used peptides and antibodies can be modified to improve their therapeutic potential. As p...
Conjugation of proteins to well-defined polymers is a promising strategy for developing effective ta...
Polymer–peptide conjugates (also known as biohybrids) are attracting considerable attention as injec...
Linear polyether polyol (PEP) consisting of glycidol as repeating units is a flexible hydrophilic al...
Polyethylene glycol (PEG) at the moment is considered the leading polymer for protein conjugation in...
The field of drug delivery is fast expanding and its potentials have already been proved by the many...
Bioconjugates play an important role in several fields of biomolecular and bio-medicinal sciences. P...
A tri(ethylene glycol)-containing lactide analogue was synthesized via thiol–ene chemistry between ...
Poly(ethylene glycol)s grated onto suitably functionalized, crosslinked polystyrenes were introduced...