In times of genetically modified food, globalized production and distribution chains, food safety is a major issue in public policy. Although industrial actors have traditionally had remarkable influence on political decision- making in this area, challenger organizations from civil society have gained influence by mobilizing support and shaping public discourse on the Internet. The authors’ study analyzes online issue networks concerning food safety in order to assess the actor constellations and coalitions that may serve as an opportunity structure for the mobilization of the issue. By comparing the US, the UK, Germany, and Switzerland, the authors investigate the differences in policy settings between pluralist and corporatist d...