Einleitung Die Mycophenolsäure (MPA) gehört zur standardmäßigen immunsuppressiven Therapie nach Nierentransplantation. Es gibt nur wenige prospektive Studien zur Überprüfung der Eignung von Dosisschemata für eine Therapie mit Mycophenolatmofetil. Mit dieser Arbeit sollte überprüft werden, ob durch Therapeutisches Drug Monitoring der Mycophenolsäure im ersten Jahr nach Nierentransplantation das klinische Outcome verbessert werden kann. Außerdem wurde im Rahmen einer Substudie die Bedeutung der IMPDH-Aktivität für das Monitoring der MPA-Pharmakodynamik untersucht. Methodik Die Untersuchungen erfolgten im Rahmen einer offenen, prospektiven, randomisierten, kontrollierten, multizentrischen Studie (FDCC-Studie). Alle Patienten wurden zentral ran...
used in organ transplantation to prevent acute rejection. Because MMF can produce hematologic and/or...
The description more than 30 years ago of the role of de novo purine synthesis in T and B lymphocyte...
Mycophenolate drug levels are decreased by co-administration of cyclosporine. However, mycophenolate...
Mycophenolate mofetil (MMF) is an immunosuppressive drug used to prevent rejection following solid o...
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32393Mycophenolate mofetil (MMF), an...
This review aims to provide an extensive overview of the literature on the clinical pharmacokinetics...
The mycophenolate mofetil (MMF) dose management for optimization of post-transplant treatment especi...
Die Therapie mit Calcineurin-Inhibitoren (CNI) in Kombination mit Mycophenolat (MPA) und Methylpredn...
Mycophenolate mofetil (MMF) is the preferred antimetabolite in solid organ transplantation. It is a ...
BACKGROUND: Mycophenolic acid (MPA) is widely used as part of immunosuppressive regimens following a...
Immunosuppressive therapy is the backbone to renal transplantation. Although an adequate level of im...
The concentration-effect relationship for mycophenolic acid (MPA), and the high variability in MPA c...
This review aims to provide an update of the literature on the pharmacology and toxicology of mycoph...
AbstractWe evaluated the pharmacodynamic relationships between mycophenolic acid (MPA), the active m...
O número de transplantados idosos aumentou desde a última década. No entanto, a farmacocinética do á...
used in organ transplantation to prevent acute rejection. Because MMF can produce hematologic and/or...
The description more than 30 years ago of the role of de novo purine synthesis in T and B lymphocyte...
Mycophenolate drug levels are decreased by co-administration of cyclosporine. However, mycophenolate...
Mycophenolate mofetil (MMF) is an immunosuppressive drug used to prevent rejection following solid o...
Podeu consultar el llibre complet a: http://hdl.handle.net/2445/32393Mycophenolate mofetil (MMF), an...
This review aims to provide an extensive overview of the literature on the clinical pharmacokinetics...
The mycophenolate mofetil (MMF) dose management for optimization of post-transplant treatment especi...
Die Therapie mit Calcineurin-Inhibitoren (CNI) in Kombination mit Mycophenolat (MPA) und Methylpredn...
Mycophenolate mofetil (MMF) is the preferred antimetabolite in solid organ transplantation. It is a ...
BACKGROUND: Mycophenolic acid (MPA) is widely used as part of immunosuppressive regimens following a...
Immunosuppressive therapy is the backbone to renal transplantation. Although an adequate level of im...
The concentration-effect relationship for mycophenolic acid (MPA), and the high variability in MPA c...
This review aims to provide an update of the literature on the pharmacology and toxicology of mycoph...
AbstractWe evaluated the pharmacodynamic relationships between mycophenolic acid (MPA), the active m...
O número de transplantados idosos aumentou desde a última década. No entanto, a farmacocinética do á...
used in organ transplantation to prevent acute rejection. Because MMF can produce hematologic and/or...
The description more than 30 years ago of the role of de novo purine synthesis in T and B lymphocyte...
Mycophenolate drug levels are decreased by co-administration of cyclosporine. However, mycophenolate...