Hematopoietic stem cells (HSCs) are responsible for the production of all mature hematopoietic cells during the entire life of an organism. It is now known that HSCs are generated from a specific subset of endothelial cells in the main arteries of the developing mouse and zebrafish embryos. In the aorta of the mouse embryo, HSCs are first detected as part of intra-aortic hematopoietic clusters, transient small aggregates of cells in contact with the blood circulation. In the zebrafish embryo, HSCs undergo a sub-aortic ingression before being released into the blood stream. In both species, HSCs are later amplified in secondary sites before migrating to the bone or kidney marrow where they will reside during adulthood. In the past ten years,...
The transcriptional programs that govern hematopoiesis have been investigated primarily by populatio...
SummaryThe transcriptional programs that govern hematopoiesis have been investigated primarily by po...
<div><p>Although several reports have characterized the hematopoietic stem cell (HSC) transcriptome,...
Hematopoietic stem cells (HSCs) are responsible for the production of all mature hematopoietic cells...
In vertebrates, haematopoiesis occurs in two waves. The primitive wave gives rise to transient myelo...
Haematopoietic stem cells (HSCs) arise in the developing aorta during embryogenesis. The number of H...
Haematopoietic stem cells (HSCs) are generated from haemogenic endothelial (HE) cells via the format...
Haematopoietic stem cells (HSCs) arise in the developing aorta during embryogenesis. The number of H...
Although several reports have characterized the hematopoietic stem cell (HSC) transcriptome, the rol...
Summary: In vertebrates, hematopoiesis occurring in different niches is orchestrated by intrinsic an...
In vertebrates, haematopoietic stem cells (HSCs) maintain the blood system throughout life. HSCs are...
The success of marker-based approaches for dissecting haematopoiesis in mouse and human is reliant o...
Although several reports have characterized the hematopoietic stem cell (HSC) transcriptome, the rol...
The transcriptional programs that govern hematopoiesis have been investigated primarily by populatio...
Hematopoietic stem cells (HSCs) sustain blood production throughout life and are of pivotal importan...
The transcriptional programs that govern hematopoiesis have been investigated primarily by populatio...
SummaryThe transcriptional programs that govern hematopoiesis have been investigated primarily by po...
<div><p>Although several reports have characterized the hematopoietic stem cell (HSC) transcriptome,...
Hematopoietic stem cells (HSCs) are responsible for the production of all mature hematopoietic cells...
In vertebrates, haematopoiesis occurs in two waves. The primitive wave gives rise to transient myelo...
Haematopoietic stem cells (HSCs) arise in the developing aorta during embryogenesis. The number of H...
Haematopoietic stem cells (HSCs) are generated from haemogenic endothelial (HE) cells via the format...
Haematopoietic stem cells (HSCs) arise in the developing aorta during embryogenesis. The number of H...
Although several reports have characterized the hematopoietic stem cell (HSC) transcriptome, the rol...
Summary: In vertebrates, hematopoiesis occurring in different niches is orchestrated by intrinsic an...
In vertebrates, haematopoietic stem cells (HSCs) maintain the blood system throughout life. HSCs are...
The success of marker-based approaches for dissecting haematopoiesis in mouse and human is reliant o...
Although several reports have characterized the hematopoietic stem cell (HSC) transcriptome, the rol...
The transcriptional programs that govern hematopoiesis have been investigated primarily by populatio...
Hematopoietic stem cells (HSCs) sustain blood production throughout life and are of pivotal importan...
The transcriptional programs that govern hematopoiesis have been investigated primarily by populatio...
SummaryThe transcriptional programs that govern hematopoiesis have been investigated primarily by po...
<div><p>Although several reports have characterized the hematopoietic stem cell (HSC) transcriptome,...