KPC-like carbapenemase-producing enterobacteriaceae colonizing patients in Europe and Israel
- Baraniak, A.
- Izdebski, R.
- Fiett, J.
- Herda, M.
- Derde, L. P G
- Bonten, M. J M
- Adler, A.
- Carmeli, Y.
- Goossens, H.
- Hryniewicz, W.
- Brun-Buisson, C.
- Gniadkowski, M.
DOIAbstract
In a 2008-2011 survey, 17,945 patients in 18 hospital units in Europe and Israel were screened for carriage of Klebsiella pneumoniae carbapenemase (KPC)-producing Enterobacteriaceae, resulting in identification of 124 positive patients. The isolates were dominated by Klebsiella pneumoniae sequence type 258 (ST258) KPC-2 and ST512 KPC-3, mainly from Greece and Italy, respectively, whereas Israeli isolates were of diverse species, clones, and KPC variants. Various blaKPC platforms were observed, among which IncFIIK-FIBK plasmids with blaKPC-2/-3 genes in the Tn4401a transposon prevailed
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