Add to ORKGWithin the hippocampal formation, two forms of long-lasting synaptic plasticity, long-term potentiation (LTP) and long-term depression (LTD), can be induced which require the activation of NMDA receptors. Interestingly, it has been shown that both LTP and LTD are reduced in adult animals. Recently, a new chemical protocol has been described which elicits LTD in the CA1 field of the hippocampus. Application of 20 m NMDA for 3 min results in a stable and long-lasting decrease in the evoked synaptic responses. We used this protocol to induce LTD in hippocampal slices from young and adult rats and show that this form of LTD is AP5-sensitive and can be blocked by the protein phosphatase inhibitor cyclosporin A in slices from adult animals. In co...
Two distinct forms of long-term depression (LTD), one dependent on the activation of NMDA receptors ...
Two distinct forms of long-term depression (LTD), one dependent on the activation of NMDA receptors ...
Two distinct forms of long-term depression (LTD), one dependent on the activation of NMDA receptors ...
Within the hippocampal formation, two forms of long-lasting synaptic plasticity, long-term potentiat...
In young rats, low frequency (1-2 Hz) stimulation of the Schaffer collaterals for 15 min induces in ...
Long-term potentiation (LTP) and depression (LTD) are important forms of activity-dependent synaptic...
Long-term potentiation (LTP) and depression (LTD) are important forms of activity-dependent synaptic...
Synaptic plasticity has long been considered as a cellular basis for learning and memory. The most p...
Long-term potentiation (LTP) and long-term depression (LTD) are forms of synaptic plasticity thought...
We have found that two distinct forms of long-term depression (LTD), one dependent on the activation...
We have found that two distinct forms of long-term depression (LTD), one dependent on the activation...
We have found that two distinct forms of long-term depression (LTD), one dependent on the activation...
We have found that two distinct forms of long-term depression (LTD), one dependent on the activation...
AbstractTwo distinct forms of long-term depression (LTD), one dependent on the activation of NMDA re...
We have found that two distinct forms of long-term depression (LTD), one dependent on the activation...
Two distinct forms of long-term depression (LTD), one dependent on the activation of NMDA receptors ...
Two distinct forms of long-term depression (LTD), one dependent on the activation of NMDA receptors ...
Two distinct forms of long-term depression (LTD), one dependent on the activation of NMDA receptors ...
Within the hippocampal formation, two forms of long-lasting synaptic plasticity, long-term potentiat...
In young rats, low frequency (1-2 Hz) stimulation of the Schaffer collaterals for 15 min induces in ...
Long-term potentiation (LTP) and depression (LTD) are important forms of activity-dependent synaptic...
Long-term potentiation (LTP) and depression (LTD) are important forms of activity-dependent synaptic...
Synaptic plasticity has long been considered as a cellular basis for learning and memory. The most p...
Long-term potentiation (LTP) and long-term depression (LTD) are forms of synaptic plasticity thought...
We have found that two distinct forms of long-term depression (LTD), one dependent on the activation...
We have found that two distinct forms of long-term depression (LTD), one dependent on the activation...
We have found that two distinct forms of long-term depression (LTD), one dependent on the activation...
We have found that two distinct forms of long-term depression (LTD), one dependent on the activation...
AbstractTwo distinct forms of long-term depression (LTD), one dependent on the activation of NMDA re...
We have found that two distinct forms of long-term depression (LTD), one dependent on the activation...
Two distinct forms of long-term depression (LTD), one dependent on the activation of NMDA receptors ...
Two distinct forms of long-term depression (LTD), one dependent on the activation of NMDA receptors ...
Two distinct forms of long-term depression (LTD), one dependent on the activation of NMDA receptors ...