Partitioning of chromatids during mitosis requires that chromosome compaction and spindle length scale appropriately with each other. However, it is not clear whether chromosome condensation and spindle elongation are linked. Here we have used chromosome fusions to examine the impact of increased chromosome length during yeast mitosis. We find that yeast cells could cope with a >50% increase in the length of their longest chromosome arm by decreasing the physical length of the mitotic chromosome arm through 1) reducing the number of copies of the repetitive rDNA array and 2) by increasing the level of mitotic condensation. Consistently, cells carrying the fused chromosomes became more sensitive to loss of condensin- and its regula...
SummaryMetaphase describes a phase of mitosis where chromosomes are attached and oriented on the bip...
Mitosis is a key event in the life of a cell, where duplicated chromosomes are separated into the da...
AbstractSister chromatid cohesion and chromosome condensation are both essential to the successful c...
SummarySpatial and temporal coordination of mitotic events has been generally attributed to the coin...
SummaryMetaphase describes a phase of mitosis where chromosomes are attached and oriented on the bip...
During cellular division, chromosomes undergo a series of cytological events that allow for the main...
During cellular division, chromosomes undergo a series of cytological events that allow for the main...
The segregation of eukaryotic chromosomes during mitosis requires their extensive folding into units...
The length of the mitotic spindle varies among different cell types. A simple model for spindle leng...
Abstract The segregation of eukaryotic chromosomes during mitosis requires their extensive folding i...
Summary: Eukaryotic cells inherit their genomes in the form of chromosomes, which are formed from th...
A characteristic feature of mitotic spindles is the congression of chromosomes near the spindle equa...
Eukaryotic chromosomes reach their stable rod-shaped appearance in mitosis in a reaction dependent o...
The dynamic reorganization of chromatin into rigid and compact mitotic chromosomes is of fundamental...
Mitosis is a key event in the life of a cell, where duplicated chromosomes are separated into the da...
SummaryMetaphase describes a phase of mitosis where chromosomes are attached and oriented on the bip...
Mitosis is a key event in the life of a cell, where duplicated chromosomes are separated into the da...
AbstractSister chromatid cohesion and chromosome condensation are both essential to the successful c...
SummarySpatial and temporal coordination of mitotic events has been generally attributed to the coin...
SummaryMetaphase describes a phase of mitosis where chromosomes are attached and oriented on the bip...
During cellular division, chromosomes undergo a series of cytological events that allow for the main...
During cellular division, chromosomes undergo a series of cytological events that allow for the main...
The segregation of eukaryotic chromosomes during mitosis requires their extensive folding into units...
The length of the mitotic spindle varies among different cell types. A simple model for spindle leng...
Abstract The segregation of eukaryotic chromosomes during mitosis requires their extensive folding i...
Summary: Eukaryotic cells inherit their genomes in the form of chromosomes, which are formed from th...
A characteristic feature of mitotic spindles is the congression of chromosomes near the spindle equa...
Eukaryotic chromosomes reach their stable rod-shaped appearance in mitosis in a reaction dependent o...
The dynamic reorganization of chromatin into rigid and compact mitotic chromosomes is of fundamental...
Mitosis is a key event in the life of a cell, where duplicated chromosomes are separated into the da...
SummaryMetaphase describes a phase of mitosis where chromosomes are attached and oriented on the bip...
Mitosis is a key event in the life of a cell, where duplicated chromosomes are separated into the da...
AbstractSister chromatid cohesion and chromosome condensation are both essential to the successful c...