i(7)(q10) in myeloid malignancies

Isochromosome of the long arm of chromosome 7 is a known chromosomal abnormality in hematological malignancies that may be found in patients with Shwachman-Diamond syndrome, hepatosplenic T-cell lymphoma and acute lymphoblastic leukemia. In myeloid malignancies, i(7)(q10) may be found in acute myeloid leukemias and chronic myeloproliferative disorders, either as a solely anomaly or more frequently as a secondary anomaly associated with other additional anomalies