The design and synthesis of spirocycles is a challenging task because it involves the creation of a quaternary center, which itself is considered to be one of the most difficult tasks among synthetic transformations. Some recent approaches based on metathesis, cycloaddition and transition-metal-mediated transformations to spirocycles are described here
A variety of spirocyclic heterocycles have been constructed by a double-alkylation and reductive cyc...
A methodology for the synthesis of novel spiro-cyclohexene bicyclo [2.2.2] octane derivatives, inclu...
This letter details the formation of 18-membered macrocyclic spirocyclic esters and ethers from read...
In this account we disclose a variety of simple strategies demonstrated in our laboratory in the las...
The synthesis of complex molecules is one of the most challenging goals for synthetic chemists. The ...
We have demonstrated a simple and an efficient method for the synthesis of spirocycles starting with...
Various spiro-cyclic systems were synthesized by utilizing ring-closing metathesis as a key step. Th...
The formation of quaternary centers is a formidable challenge. Once these quaternary centers become ...
The development of complexity-generating reactions for the synthesis of molecules containing multipl...
A comprehensive treatment of the latest research in, and applications of, spiro compoundsSpiro Compo...
Synthesis of diverse spiro-heterocyclic compounds via the ring-closing (RCM) metathesis approach is ...
1099-1106Diverse and intricate bis-spirocycles have been assembled via a Grignard reaction and ring-...
2,6-Disubstituted spiro[3.3]heptanes were synthesized to investigate and develop synthetic methods f...
Spiro-compounds. Part I. A New Route to Spiro compounds. Synthesis of cycloHexane-spiro- cyclopenta...
International audienceFrom their discovery in the late 1960s, iminosugars have undergone an expansio...
A variety of spirocyclic heterocycles have been constructed by a double-alkylation and reductive cyc...
A methodology for the synthesis of novel spiro-cyclohexene bicyclo [2.2.2] octane derivatives, inclu...
This letter details the formation of 18-membered macrocyclic spirocyclic esters and ethers from read...
In this account we disclose a variety of simple strategies demonstrated in our laboratory in the las...
The synthesis of complex molecules is one of the most challenging goals for synthetic chemists. The ...
We have demonstrated a simple and an efficient method for the synthesis of spirocycles starting with...
Various spiro-cyclic systems were synthesized by utilizing ring-closing metathesis as a key step. Th...
The formation of quaternary centers is a formidable challenge. Once these quaternary centers become ...
The development of complexity-generating reactions for the synthesis of molecules containing multipl...
A comprehensive treatment of the latest research in, and applications of, spiro compoundsSpiro Compo...
Synthesis of diverse spiro-heterocyclic compounds via the ring-closing (RCM) metathesis approach is ...
1099-1106Diverse and intricate bis-spirocycles have been assembled via a Grignard reaction and ring-...
2,6-Disubstituted spiro[3.3]heptanes were synthesized to investigate and develop synthetic methods f...
Spiro-compounds. Part I. A New Route to Spiro compounds. Synthesis of cycloHexane-spiro- cyclopenta...
International audienceFrom their discovery in the late 1960s, iminosugars have undergone an expansio...
A variety of spirocyclic heterocycles have been constructed by a double-alkylation and reductive cyc...
A methodology for the synthesis of novel spiro-cyclohexene bicyclo [2.2.2] octane derivatives, inclu...
This letter details the formation of 18-membered macrocyclic spirocyclic esters and ethers from read...
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