Azithromycin (AZM) is a macrolide antibiotic used for the treatment of a number of bacterial infections. It is known to have a low oral bioavailability (37 %) due to its relatively high molecular weight, incomplete solubility and/or poor intestinal permeability, which is potentially restricting its intestinal absorption. To overcome these drawbacks liquid and solid self-emulsifying drug delivery systems (L-SEDDs and S-SEDDs) of AZM were prepared in an attempt to enhance its solubility, and altering its cellular penetration, which might improve its oral bioavailability
Approximately half of the new drug applicants that reach formulation have poor water solubility. Ora...
Azithromycin is the drug of choice in the treatment of several bacterial infections, most often thos...
© 2019, © 2019 Taylor & Francis Group, LLC. This study aimed to develop solid self-microemulsifying ...
There are approximately 40% of new drug molecules discovered and some drugmolecules that are availab...
Objective: Azithromycin (AZM), an azalide drug is used to treat bacterial infections. It is poorly w...
Oral route is the easiest and most convenient route for drug administration. Oral drug delivery syst...
Azithromycin (AZM) is a poorly soluble macrolide antibacterial agent. Its low solubility is conside...
By dissolving drug molecules in these solutions, a unit dosage form for oral administration can be g...
This study explored the design of supersaturable self-microemulsifying drug delivery systems (S-SMED...
Zidovudine (AZT) mucoadhesive solid dispersions (SD) were prepared using a sodium starch glycolate (...
Self-emulsifying drug delivery systems (SEDDS) have been mainly investigated to enhance the oral bio...
Thesis (PhD (Pharmaceutics))--North-West University, Potchefstroom Campus, 2013Azithromycin, an azal...
The self-microemulsifying drug delivery system (SMEDDS) was employed to improve the bioavailability...
Oral route has always been the favorite route of drug administration in many diseases and till today...
The use of the oral route of administration for the treatment of young children with antibiotics can...
Approximately half of the new drug applicants that reach formulation have poor water solubility. Ora...
Azithromycin is the drug of choice in the treatment of several bacterial infections, most often thos...
© 2019, © 2019 Taylor & Francis Group, LLC. This study aimed to develop solid self-microemulsifying ...
There are approximately 40% of new drug molecules discovered and some drugmolecules that are availab...
Objective: Azithromycin (AZM), an azalide drug is used to treat bacterial infections. It is poorly w...
Oral route is the easiest and most convenient route for drug administration. Oral drug delivery syst...
Azithromycin (AZM) is a poorly soluble macrolide antibacterial agent. Its low solubility is conside...
By dissolving drug molecules in these solutions, a unit dosage form for oral administration can be g...
This study explored the design of supersaturable self-microemulsifying drug delivery systems (S-SMED...
Zidovudine (AZT) mucoadhesive solid dispersions (SD) were prepared using a sodium starch glycolate (...
Self-emulsifying drug delivery systems (SEDDS) have been mainly investigated to enhance the oral bio...
Thesis (PhD (Pharmaceutics))--North-West University, Potchefstroom Campus, 2013Azithromycin, an azal...
The self-microemulsifying drug delivery system (SMEDDS) was employed to improve the bioavailability...
Oral route has always been the favorite route of drug administration in many diseases and till today...
The use of the oral route of administration for the treatment of young children with antibiotics can...
Approximately half of the new drug applicants that reach formulation have poor water solubility. Ora...
Azithromycin is the drug of choice in the treatment of several bacterial infections, most often thos...
© 2019, © 2019 Taylor & Francis Group, LLC. This study aimed to develop solid self-microemulsifying ...