Add to ORKGTuberculosis (TB), caused by Mycobacterium tuberculosis is a leading killer that has plagued mankind for centuries. The disease is estimated to infect 8 million and kill 2 - 3 million people each year (Rouse et al., 1995; Manca et al., 1997). A frequently used drug to treat TB is isonicotinic acid hydrazide (INH/ isoniazid) but unfortunately, INHresistant M. tuberculosis organisms are becoming quite common now
Tuberculosis is found among the main causes of mortality in the World, although is a neglected disea...
The enoyl-ACP reductase enzyme (InhA) from M. tuberculosis is recognized as the primary target of is...
Objectives: Enoyl acyl-carrier-protein reductase (InhA), the primary endogenous target for isoniazid...
AbstractObjective/BackgroundIsoniazid (INH) is one of the effective antituberculosis (TB) drugs used...
AbstractTuberculosis (TB) is an ancient disease caused by Mycobacterium tuberculosis (MTB), which re...
Antimicrobial resistance represents a growing global health problem. The emergence of novel resistan...
Isoniazid is an important antitubercular molecule identified as a drug of choice in tuberculosis tre...
AbstractThe increasing prevalence of tuberculosis in many areas of the world, associated with the ri...
Isoniazid, an important drug in the anti-tuberculosis therapy, the enzyme catalase-peroxidase (KatG...
The resistance strains of Mycobacterium tuberculosis have complicated the tuberculosis management an...
The resumption of tuberculosis led to an increased need to understand the molecular mechanisms of dr...
An understanding of isoniazid (INH) drug resistance mechanism in Mycobacterium tuberculosis should p...
Millions of individuals are infected with and die from tuberculosis (TB) each year. There is an inc...
Isoniazid (INH) is usually administered to treat latent Mycobacterium tuberculosis (<i>Mtb</i>) infe...
International audienceInhA (Enoyl-ACP reductase) plays a crucial role in the biosynthetic pathway of...
Tuberculosis is found among the main causes of mortality in the World, although is a neglected disea...
The enoyl-ACP reductase enzyme (InhA) from M. tuberculosis is recognized as the primary target of is...
Objectives: Enoyl acyl-carrier-protein reductase (InhA), the primary endogenous target for isoniazid...
AbstractObjective/BackgroundIsoniazid (INH) is one of the effective antituberculosis (TB) drugs used...
AbstractTuberculosis (TB) is an ancient disease caused by Mycobacterium tuberculosis (MTB), which re...
Antimicrobial resistance represents a growing global health problem. The emergence of novel resistan...
Isoniazid is an important antitubercular molecule identified as a drug of choice in tuberculosis tre...
AbstractThe increasing prevalence of tuberculosis in many areas of the world, associated with the ri...
Isoniazid, an important drug in the anti-tuberculosis therapy, the enzyme catalase-peroxidase (KatG...
The resistance strains of Mycobacterium tuberculosis have complicated the tuberculosis management an...
The resumption of tuberculosis led to an increased need to understand the molecular mechanisms of dr...
An understanding of isoniazid (INH) drug resistance mechanism in Mycobacterium tuberculosis should p...
Millions of individuals are infected with and die from tuberculosis (TB) each year. There is an inc...
Isoniazid (INH) is usually administered to treat latent Mycobacterium tuberculosis (<i>Mtb</i>) infe...
International audienceInhA (Enoyl-ACP reductase) plays a crucial role in the biosynthetic pathway of...
Tuberculosis is found among the main causes of mortality in the World, although is a neglected disea...
The enoyl-ACP reductase enzyme (InhA) from M. tuberculosis is recognized as the primary target of is...
Objectives: Enoyl acyl-carrier-protein reductase (InhA), the primary endogenous target for isoniazid...