International audienceLacZ DNA and LacZ RNA were microinjected during the first cleavages of embryos. LacZ DNA was not expressed before 18-19 h post insemination (hpi) but LacZ RNA was translated. Before 22 hpi LacZ DNA was expressed in the pronuclei of the one-cell embryos and the polypeptides of the minor, but not the major activation period of the genome were synthesized. This suggests a negative control of transcription before 18-19 hpi and demonstrates that its resumption is independent of the first cleavage and of the major activation of the genome. At the time of the minor activation the eggs contain the trans-acting elements to express a variety of genes that they do not express. It may indicate that, the minor and the major activat...
AbstractIn the mouse embryo, the onset of zygotic transcription occurs at the end of the first cell ...
Methylation of genomic DNA at CpG sequences has a repressive effect on gene expression in vertebrate...
Transcription of exogenous DNA templates in mouse ovarian oocytes was investigated by microinjecting...
International audienceLacZ DNA and LacZ RNA were microinjected during the first cleavages of embryos...
International audienceIn the mouse, transcriptional permissiveness is established in the fertilized ...
AbstractTranscription of endogenous genes in preimplantation 1- and 2-cell mouse embryos was determi...
Fertilization is a very complex biological process that requires the perfect cooperation between two...
Fertilization is a very complex biological process that requires the perfect cooperation between two...
International audienceThe mouse zygotic genome is activated at the 2-cell stage. At this stage, micr...
The 2-cell stage of mouse embryogenesis is characterized by two phases of alpha-amanitin-sensitive p...
International audienceIn the mouse embryo, the onset of zygotic transcription occurs at the end of t...
Neganova I, Augustin M, Eichenlaub-Ritter U, Jockusch H. Maternal versus paternal expression of a La...
Mouse preimplantation development is marked with pronounced changes in the patterns of reprogramming...
The preimplantation period of embryogenesis is crucial during mammalian ontogenesis. During this per...
The time of onset of gene transcription in the mouse embryo is temporally regulated. A prominent fea...
AbstractIn the mouse embryo, the onset of zygotic transcription occurs at the end of the first cell ...
Methylation of genomic DNA at CpG sequences has a repressive effect on gene expression in vertebrate...
Transcription of exogenous DNA templates in mouse ovarian oocytes was investigated by microinjecting...
International audienceLacZ DNA and LacZ RNA were microinjected during the first cleavages of embryos...
International audienceIn the mouse, transcriptional permissiveness is established in the fertilized ...
AbstractTranscription of endogenous genes in preimplantation 1- and 2-cell mouse embryos was determi...
Fertilization is a very complex biological process that requires the perfect cooperation between two...
Fertilization is a very complex biological process that requires the perfect cooperation between two...
International audienceThe mouse zygotic genome is activated at the 2-cell stage. At this stage, micr...
The 2-cell stage of mouse embryogenesis is characterized by two phases of alpha-amanitin-sensitive p...
International audienceIn the mouse embryo, the onset of zygotic transcription occurs at the end of t...
Neganova I, Augustin M, Eichenlaub-Ritter U, Jockusch H. Maternal versus paternal expression of a La...
Mouse preimplantation development is marked with pronounced changes in the patterns of reprogramming...
The preimplantation period of embryogenesis is crucial during mammalian ontogenesis. During this per...
The time of onset of gene transcription in the mouse embryo is temporally regulated. A prominent fea...
AbstractIn the mouse embryo, the onset of zygotic transcription occurs at the end of the first cell ...
Methylation of genomic DNA at CpG sequences has a repressive effect on gene expression in vertebrate...
Transcription of exogenous DNA templates in mouse ovarian oocytes was investigated by microinjecting...