Tuberculosis (TB) remains a serious public health threat worldwide. Theoretically ultimate resolution of whole genome sequencing (WGS) for Mycobacterium tuberculosis complex (MTBC) strain classification makes this technology very attractive for epidemiological investigations. To summarise the evidence available in peer-reviewed publications on the role and place of WGS in detection of TB transmission. 69 peer-reviewed publications identified in Pubmed database. Evidence from >30 publications suggests that a cut-off value of <6 single nucleotide polymorphisms (SNPs) between strains efficiently excludes cases that are not the result of recent transmission and could be used for the identification of drug-sensitive isolates involved in direct h...
Mycobacterium tuberculosis drug resistance is a threat to global tuberculosis (TB) control. Comprehe...
The control of tuberculosis depends on the identification and treatment of infectious patients and t...
Tuberculosis (TB) is a global infectious threat that is intensified by an increasing incidence of hi...
Contact tracing complemented with genotyping is considered an important means of understanding perso...
Contact investigations following the diagnosis of active tuberculosis (TB) are paramount for the con...
We used whole-genome sequencing (WGS) to delineate transmission networks and investigate the benefit...
In 2013 an estimated 9 million patients were diagnosed with tuberculosis across the globe, leading t...
A large isoniazid-resistant tuberculosis outbreak centred on London, United Kingdom, has been ongoin...
Whole genome sequencing (WGS) can help to relate Mycobacterium tuberculosis genomes to one another t...
9 páginas, 3 figurasBackground Direct whole-genome sequencing of Mycobacterium tuberculosis from cli...
The implementation of next generation sequencing techniques, such as whole genome sequencing (WGS), ...
AbstractIn the past two decades, DNA techniques have been increasingly used in the laboratory diagno...
AbstractThe control of tuberculosis depends on the identification and treatment of infectious patien...
The control of tuberculosis depends on the identification and treatment of infectious patients and t...
Background: Understanding Mycobacterium tuberculosis (Mtb) transmission is essential to guide eff...
Mycobacterium tuberculosis drug resistance is a threat to global tuberculosis (TB) control. Comprehe...
The control of tuberculosis depends on the identification and treatment of infectious patients and t...
Tuberculosis (TB) is a global infectious threat that is intensified by an increasing incidence of hi...
Contact tracing complemented with genotyping is considered an important means of understanding perso...
Contact investigations following the diagnosis of active tuberculosis (TB) are paramount for the con...
We used whole-genome sequencing (WGS) to delineate transmission networks and investigate the benefit...
In 2013 an estimated 9 million patients were diagnosed with tuberculosis across the globe, leading t...
A large isoniazid-resistant tuberculosis outbreak centred on London, United Kingdom, has been ongoin...
Whole genome sequencing (WGS) can help to relate Mycobacterium tuberculosis genomes to one another t...
9 páginas, 3 figurasBackground Direct whole-genome sequencing of Mycobacterium tuberculosis from cli...
The implementation of next generation sequencing techniques, such as whole genome sequencing (WGS), ...
AbstractIn the past two decades, DNA techniques have been increasingly used in the laboratory diagno...
AbstractThe control of tuberculosis depends on the identification and treatment of infectious patien...
The control of tuberculosis depends on the identification and treatment of infectious patients and t...
Background: Understanding Mycobacterium tuberculosis (Mtb) transmission is essential to guide eff...
Mycobacterium tuberculosis drug resistance is a threat to global tuberculosis (TB) control. Comprehe...
The control of tuberculosis depends on the identification and treatment of infectious patients and t...
Tuberculosis (TB) is a global infectious threat that is intensified by an increasing incidence of hi...