Multicenter comparison of the etest and EUCAST methods for antifungal susceptibility testing of Candida isolates to micafungin
- Bougnoux, M.-E.
- Dannaoui, E.
- Accoceberry, I.
- Angoulvant, A.
- Bailly, E.
- Botterel, F.
- Chevrier, S.
- Chouaki, T.
- Cornet, M.
- Dalle, F.
- Datry, A.
- Dupuis, A.
- Fekkar, A.
- Gangneux, J.P.
- Guitard, J.
- Hennequin, C.
- Le Govic, Y.
- Le Pape, P.
- Maubon, D.
- Ranque, S.
- Sautour, M.
- Sendid, B.
- Chandenier, J.
DOIAbstract
International audienceIn vitro susceptibility of 933 Candida isolates, from 16 French hospitals, to micafungin was determined using the Etest in each center. All isolates were then sent to a single center for determination of MICs by the EUCAST reference method. Overall essential agreement between the two tests was 98.5% at ±2 log2 dilutions and 90.2% at ±1 log2 dilutions. Categorical agreement was 98.2%. The Etest is a valuable alternative to EUCAST for the routine determination of micafungin MICs in medical mycology laboratories. Copyright © 2016, American Society for Microbiology. All Rights Reserved
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