We consider statistical inference in the presence of serial dependence. The main focus is on use of statistics that are constructed as if no dependence were believed present, and are asymptotically normal in the presence of dependence. Typically the variance in the limit distribution is affected by the dependence, and needs to be consistently estimated. We discuss first the leading caes of location and regression models, stressing least squares estimation. We then consider the use of robust estimates, such as M-estimates, in these models. We go on to discuss more general statistical models, including econometric models. The rules of inference adopted in these cases typically involve use of a bandwidth or smoothing number when the dependence...