Squamous cell carcinoma of the lung is a common cancer with 95% mortality at 5 years. These cancers arise from preinvasive lesions, which have a natural history of development progressing through increasing severity of dysplasia to carcinoma in situ (CIS), and in some cases, ending in transformation to invasive carcinoma. Synchronous preinvasive lesions identified at autopsy have been previously shown to be clonally related
Background: Among patients with non-small-cell lung cancer (NSCLC), data on intratumor heterogeneity...
Patients with a primary cancer in the lung or in the upper aerodigestive tract have an increased ris...
Carcinomas are believed to develop by incremental steps of increasingly abnormal morphology driven b...
Background Squamous cell carcinoma of the lung is a common cancer with 95% mortality at 5 years. The...
BACKGROUND: Lung cancer is the most common cause of cancer death in the United States. Multiple anat...
The molecular alterations that occur in cells before cancer is manifest are largely uncharted. Lung ...
Squamous cell lung cancers are amongst the most mutated cancers known. Their cells exhibit a high bu...
Lung cancer is the leading cause of cancer deaths for people of both sexes worldwide. Early diagnosi...
Spatial and temporal dissection of the genomic changes occurring during the evolution of human non-s...
BACKGROUND: The natural history of bronchial preinvasive lesions and the risk of developing lung can...
Basal cells are stem/progenitor cells that maintain airway homeostasis, enact repair following epith...
Lung squamous cell carcinoma (SCC) is thought to arise from premalignant lesions in the airway epith...
Adenosquamous lung tumours, which are extremely poor prognosis, may result from cellular plasticity....
The molecular alterations that occur in cells before cancer is manifest are largely uncharted. Lung ...
Background: Among patients with non–small-cell lung cancer (NSCLC), data on intratumor heterogenei...
Background: Among patients with non-small-cell lung cancer (NSCLC), data on intratumor heterogeneity...
Patients with a primary cancer in the lung or in the upper aerodigestive tract have an increased ris...
Carcinomas are believed to develop by incremental steps of increasingly abnormal morphology driven b...
Background Squamous cell carcinoma of the lung is a common cancer with 95% mortality at 5 years. The...
BACKGROUND: Lung cancer is the most common cause of cancer death in the United States. Multiple anat...
The molecular alterations that occur in cells before cancer is manifest are largely uncharted. Lung ...
Squamous cell lung cancers are amongst the most mutated cancers known. Their cells exhibit a high bu...
Lung cancer is the leading cause of cancer deaths for people of both sexes worldwide. Early diagnosi...
Spatial and temporal dissection of the genomic changes occurring during the evolution of human non-s...
BACKGROUND: The natural history of bronchial preinvasive lesions and the risk of developing lung can...
Basal cells are stem/progenitor cells that maintain airway homeostasis, enact repair following epith...
Lung squamous cell carcinoma (SCC) is thought to arise from premalignant lesions in the airway epith...
Adenosquamous lung tumours, which are extremely poor prognosis, may result from cellular plasticity....
The molecular alterations that occur in cells before cancer is manifest are largely uncharted. Lung ...
Background: Among patients with non–small-cell lung cancer (NSCLC), data on intratumor heterogenei...
Background: Among patients with non-small-cell lung cancer (NSCLC), data on intratumor heterogeneity...
Patients with a primary cancer in the lung or in the upper aerodigestive tract have an increased ris...
Carcinomas are believed to develop by incremental steps of increasingly abnormal morphology driven b...