Various tumor cells express significantly higher amounts of VIP receptors (VIPR) that provided the basis for the clinical use of radiolabeled VIP for the in vivo localization of tumors. This work studied the labeling of VIP and VIP10-28 with iodine-131 to compare the biological distribution of the labeled compounds in Nuce mice and the affinity for tumor cells. Both VIP and VIP10-28 peptides contain two tyrosine residues, in positions 10 and 22, that are theoretically equally susceptible to radioiodination employing oxidative electrophilic substitution using oxidizing agents like Chloramine T. Radiochemical purity of the reaction mixture was determined by electrophoresis and HPLC. The VIP peptide and the fragment were labeled with radioiodi...
Os tumores neuroendócrinos são raros, ocorrem principalmente no trato gastrointestinal, mas outros s...
Earlier reports described the preferential uptake of d-amino acids in tumor-bearing mice. Moreover, ...
Earlier reports described the preferential uptake of d-amino acids in tumor-bearing mice. Moreover, ...
Various tumor cells express significantly higher amounts of VIP receptors (VIPR) that provided the b...
Various tumor cells express significantly higher amounts of VIP receptors (VIPR) that provided the b...
Various tumor cells express significantly higher amounts of VIP receptors (VIPR) that provided the b...
Background: Vasoactive intestinal peptide (VIP) receptors are overexpressed in a broad variety of tu...
Copyright © 2013 Dengfeng Cheng et al. This is an open access article distributed under the Creative...
The development of nuclear medicine implies the search for new isotopes but also for new vectors spe...
The development of nuclear medicine implies the search for new isotopes but also for new vectors spe...
The development of nuclear medicine implies the search for new isotopes but also for new vectors spe...
To investigate the possibility of using radioiodine labeled framework region (FR) antisense oligonuc...
Os tumores neuroendócrinos são raros, ocorrem principalmente no trato gastrointestinal, mas outros s...
Os tumores neuroendócrinos são raros, ocorrem principalmente no trato gastrointestinal, mas outros s...
INTRODUCTION: Both A- and l-type amino acid transport are increased in tumor cells relative to norma...
Os tumores neuroendócrinos são raros, ocorrem principalmente no trato gastrointestinal, mas outros s...
Earlier reports described the preferential uptake of d-amino acids in tumor-bearing mice. Moreover, ...
Earlier reports described the preferential uptake of d-amino acids in tumor-bearing mice. Moreover, ...
Various tumor cells express significantly higher amounts of VIP receptors (VIPR) that provided the b...
Various tumor cells express significantly higher amounts of VIP receptors (VIPR) that provided the b...
Various tumor cells express significantly higher amounts of VIP receptors (VIPR) that provided the b...
Background: Vasoactive intestinal peptide (VIP) receptors are overexpressed in a broad variety of tu...
Copyright © 2013 Dengfeng Cheng et al. This is an open access article distributed under the Creative...
The development of nuclear medicine implies the search for new isotopes but also for new vectors spe...
The development of nuclear medicine implies the search for new isotopes but also for new vectors spe...
The development of nuclear medicine implies the search for new isotopes but also for new vectors spe...
To investigate the possibility of using radioiodine labeled framework region (FR) antisense oligonuc...
Os tumores neuroendócrinos são raros, ocorrem principalmente no trato gastrointestinal, mas outros s...
Os tumores neuroendócrinos são raros, ocorrem principalmente no trato gastrointestinal, mas outros s...
INTRODUCTION: Both A- and l-type amino acid transport are increased in tumor cells relative to norma...
Os tumores neuroendócrinos são raros, ocorrem principalmente no trato gastrointestinal, mas outros s...
Earlier reports described the preferential uptake of d-amino acids in tumor-bearing mice. Moreover, ...
Earlier reports described the preferential uptake of d-amino acids in tumor-bearing mice. Moreover, ...