Add to ORKGParamyosin and Sm14 are two of the six antigens selected by the World Health Organization as candidates to compose a subunit vaccine against schistosomiasis. Both antigens are recognized by individuals naturally resistant to Schistosoma mansoni infection and induced protective immunity in the murine model. Three Sm14 epitopes and eleven paramyosin epitopes were selected by their ability to bind to different HLA-DR molecules using the TEPITOPE computer program, and these peptides were synthetically produced. The cellular recognition of Sm14 and paramyosin epitopes by peripheral blood mononuclear cells of individuals living in endemic area for schistosomiasis was tested by T cell proliferation assay. Among all Sm14 and paramyosin epitopes stu...
Schistosomiasis is a parasitic disease that affects 143 million people in endemic countries. This wo...
Polypeptide surface antigens of Schistosoma mansoni recognized by schistosomiasis patients have been...
Despite advances in control via snail eradication and large-scale chemotherapy using praziquental, s...
Paramyosin and Sm14 are two of the six antigens selected by the World Health Organization as candida...
The development of a defined anti-schistosomiasis vaccine would contribute to the current control st...
Sm14 and paramyosin are two major Schistosoma mansoni vaccine candidate antigens. Recently, we have ...
Trabalho completo: acesso restrito, p. 204–212he development of a defined anti-schistosomiasis vacci...
Texto completo: acesso restrito. p. 539–547Paramyosin, a Schistosoma mansoni myoprotein associated w...
副肌球蛋白是世界卫生组织选取的用来发展血吸虫疫苗的重要候选蛋白之一.在计算机辅助下,应用PCGene程序,根据曼氏和日本血吸虫副肌球蛋白的氨基酸序列,通过对其亲水性、柔韧性、可接近性和二级结构分析预测...
Abstract Approximately 200 million people worldwide currently suffer from schistosomiasis, one of th...
Schistosomiasis is caused by the infection from Schistosoma species. Among these, Schistosoma manson...
Abstract Th1-type cytokines produced by the stimulation of Th1-type epitopes derived from defined sc...
Schistosoma japonicum paramyosin, a 97 kDa myofibrillar protein, is a recognized vaccine candidate a...
The radiation-attenuated cercarial vaccine remains the gold standard for the induction of protective...
In previous studies it was shown that the recombinant molecule, r-Sm14, induces high levels of prote...
Schistosomiasis is a parasitic disease that affects 143 million people in endemic countries. This wo...
Polypeptide surface antigens of Schistosoma mansoni recognized by schistosomiasis patients have been...
Despite advances in control via snail eradication and large-scale chemotherapy using praziquental, s...
Paramyosin and Sm14 are two of the six antigens selected by the World Health Organization as candida...
The development of a defined anti-schistosomiasis vaccine would contribute to the current control st...
Sm14 and paramyosin are two major Schistosoma mansoni vaccine candidate antigens. Recently, we have ...
Trabalho completo: acesso restrito, p. 204–212he development of a defined anti-schistosomiasis vacci...
Texto completo: acesso restrito. p. 539–547Paramyosin, a Schistosoma mansoni myoprotein associated w...
副肌球蛋白是世界卫生组织选取的用来发展血吸虫疫苗的重要候选蛋白之一.在计算机辅助下,应用PCGene程序,根据曼氏和日本血吸虫副肌球蛋白的氨基酸序列,通过对其亲水性、柔韧性、可接近性和二级结构分析预测...
Abstract Approximately 200 million people worldwide currently suffer from schistosomiasis, one of th...
Schistosomiasis is caused by the infection from Schistosoma species. Among these, Schistosoma manson...
Abstract Th1-type cytokines produced by the stimulation of Th1-type epitopes derived from defined sc...
Schistosoma japonicum paramyosin, a 97 kDa myofibrillar protein, is a recognized vaccine candidate a...
The radiation-attenuated cercarial vaccine remains the gold standard for the induction of protective...
In previous studies it was shown that the recombinant molecule, r-Sm14, induces high levels of prote...
Schistosomiasis is a parasitic disease that affects 143 million people in endemic countries. This wo...
Polypeptide surface antigens of Schistosoma mansoni recognized by schistosomiasis patients have been...
Despite advances in control via snail eradication and large-scale chemotherapy using praziquental, s...