Relationship between the frequency of meat and fish intake and the levels of hexaclorobenzene, lindane, aldrin e 4,4' dichloro diphenil 1,1' dichloroethylene, present in mamary adipose tissue samples from spanish women

Níveis de resíduos dos pesticidas organoclorados, hexaclorobenzeno (HCB), lindano gama-HCH), aldrin e 4,4'-diclorodifenil-1,1'dicloroetileno (p,p'-DDE) foram determinados em tecido adiposo mamário de mulheres residentes em Córdoba, Espanha. A maior concentração média foi detectada para o p,p'-DDE (1,869 mig/g de tecido adiposo), que estava presente em 100% das amostras. As concentrações médias de HCB, gama-HCH e aldrin encontrados foram 0,236, 0,003 e 0,006mig/g de tecido adiposo, respectivamente. Os níveis dos resíduos detectados nas amostras foram relacionados ao consumo semanal de carne e pescado pelas doadoras. O único composto cujos níveis variaram significativamente (p<FONT FACE=Symbol>£</FONT>0,05) em função da freqüência de consumo de carne foi o p,p'-DDE, tendo apresentado concentração média de 2,833 mig/g de tecido adiposo quando as doadoras relataram uma freqüência de consumo de carne superior a quatro vezes por semana.The levels of organochlorine pesticide residues <FONT FACE=Symbol>¾</FONT> hexaclorobenzene (HCB), lindane (gamma-HCH), aldrin and 4,4'dichloro diphenil 1,1'dichloroethylene (p,p'-DDE) - present in mammary adipose tissue samples from women living in Cordoba (Spain) were evaluated. The compound found at the highest concentration was p,p´-DDE (1.869(mug/g of adipose tissue), which was present in 100% of the analyzed samples. The average levels of HCB, gamma-HCH and aldrin were 0.236, 0.003 and 0.006mug/g of adipose tissue, respectively. The tissue levels of organochlorine residues were correlated with the weekly intake of meat and fish by donors. Only the tissue levels of p-p´-DDE were significantly (p<FONT FACE=Symbol>£</FONT>0.05) affected by the frequency of meat intake. Donors with a meat intake higher than four times a week presented an average level of 2.833mug/g of adipose tissue